Tamrakar Apurva Ratna, Kharel Sitaula Ranju, Joshi Sagun Narayan, Bajracharya Manjita
Phaco and Vitreo-Retinal Surgeon, Kathmandu Eye Centre, Patan, Nepal.
Department of Ophthalmology, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, B. P. Koirala Lions Centre for Ophthalmic Studies, Maharajgunj, Kathmandu, Nepal.
J Ophthalmic Inflamm Infect. 2021 Sep 22;11(1):34. doi: 10.1186/s12348-021-00265-z.
To assess the change in vision-related quality of life and psychosocial well-being of the patients with episcleritis and scleritis patients before and after treatment.
This one-and-a-half-year prospective study was conducted among 76 eyes of 71 new patients of episcleritis and scleritis. A structured questionnaire was used to assess the visual and to analyze the change in effect size. The male-to-female ratio was 1:1.536. Episcleritis was seen in 41 cases (57.7%) while scleritis was seen in 30 cases (42.3%). Patients with episcleritis had statistically significant improvement in general function score (GF) (p < 0.05) using paired t-test. The effect size showed medium improvement (approximately 0.5). Whereas there was no statistically significant change in psychosocial impact (PI), visual symptoms (VS) scoring, and a total score (p < 0.05) using paired t-test. The effect size showed no improvement for PI and total score and small improvement for VS score. Patients with scleritis had statistically significant improvement in general function score (GF), visual symptoms (VS) scoring and total score (p < 0.05) using paired-t-test. The effect size showed medium improvement (approximately 0.5) for general function score (GF) and total score. However, the effect size showed only a small improvement (approximately 0.2) for psychosocial impact (PI) score.
VisionRelated Quality of Life of patients with scleritis showed significant improvement following treatment unlike episcleritis indicating scleritis more adversely affecting psychosocial well-being.
评估前巩膜炎和巩膜炎患者治疗前后与视力相关的生活质量和心理社会幸福感的变化。
对71例新诊断的前巩膜炎和巩膜炎患者的76只眼进行了为期一年半的前瞻性研究。使用结构化问卷评估视力，并分析效应量的变化。男女比例为1:1.536。前巩膜炎41例（57.7%），巩膜炎30例（42.3%）。采用配对t检验，前巩膜炎患者的总体功能评分（GF）有统计学显著改善（p < 0.05）。效应量显示有中等程度改善（约0.5）。而采用配对t检验，心理社会影响（PI）、视觉症状（VS）评分和总分无统计学显著变化（p < 0.05）。效应量显示PI和总分无改善，VS评分有小幅度改善。采用配对t检验，巩膜炎患者的总体功能评分（GF）、视觉症状（VS）评分和总分有统计学显著改善（p < 0.05）。总体功能评分（GF）和总分的效应量显示有中等程度改善（约0.5）。然而，心理社会影响（PI）评分的效应量仅显示有小幅度改善（约0.2）。
与前巩膜炎不同，巩膜炎患者的视力相关生活质量在治疗后有显著改善，这表明巩膜炎对心理社会幸福感的负面影响更大。
