Singh Rashmi, Naranje Priyanka, Kandasamy Devasenathipathy, Jana Manisha, Gupta Aditya K, Ramateke Prashant P
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Indian J Radiol Imaging. 2021 Apr;31(2):378-382. doi: 10.1055/s-0041-1734347. Epub 2021 Jul 27.
Langerhans cell histiocytosis (LCH) is a common cause of multifocal lytic skeletal lesions in children. However, multifocal osseous tuberculosis can affect children and mimics LCH on imaging, especially in endemic regions. We report cases with atypical manifestations of multifocal osseous tuberculosis which were presumptively diagnosed as LCH. The findings of our series of cases suggest that on computed tomography (CT) irregular sclerotic margins, abscess formation, sclerosis of involved bone, and button sequestrum point toward a diagnosis of multifocal osseous tuberculosis, especially in endemic regions.
朗格汉斯细胞组织细胞增多症（LCH）是儿童多灶性溶骨性骨骼病变的常见原因。然而，多灶性骨结核也可累及儿童，且在影像学上与LCH相似，尤其是在流行地区。我们报告了一些多灶性骨结核非典型表现的病例，这些病例最初被误诊为LCH。我们系列病例的研究结果表明，在计算机断层扫描（CT）上，不规则的硬化边缘、脓肿形成、受累骨骼的硬化以及纽扣状死骨提示多灶性骨结核的诊断，尤其是在流行地区。
