Keerthi Gorantla Shravya, Pal Pravati, Pal Gopal Krushna, Sahoo Jaya Prakash, Sridhar Magadi Gopalakrishna, Balachander Jayaraman
PhD Scholar, Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Professor, Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
J Clin Diagn Res. 2017 Sep;11(9):CC10-CC14. doi: 10.7860/JCDR/2017/29307.10633. Epub 2017 Sep 1.
India has become the epicentre for diabetes, a stress-related disorder affecting the working skills and day-to-day lifestyle management of younger population. Most of the studies have reported the effect of yoga on improving Quality of Life (QoL) in diabetic patients with other comorbidities. Till date, no randomized control trial reports are available to show the effect of yoga therapy on QoL and Indian Diabetes Risk Score (IDRS) in normotensive prediabetic and diabetic young individuals.
To determine the effect of 12 weeks of yoga therapy on QoL and IDRS among normotensive prediabetic and diabetic young Indian adults.
A randomized control trial was conducted in Endocrinology Outpatient Department (OPD). Normotensive participants (n=310) aged 18-45 years were divided into healthy controls (n=62), prediabetics (n=124) and diabetics (n=124). Study group subjects were randomly assigned to Group II (n=62, prediabetes-standard treatment), Group III (n=62, prediabetes-standard treatment + yoga therapy), Group IV (n=62, diabetes-standard treatment) and Group V (n=62, diabetes-standard treatment + yoga therapy). Flanagan QoL scale, IDRS questionnaire, Fasting Plasma Glucose (FPG) and insulin were assessed pre and post 12 weeks of intervention. Statistical analysis was done using Student's paired t-test and one-way ANOVA.
Pre-post intervention analysis showed significant improvement in QoL scale with p<0.01 in Group II and Group IV; p<0.001 in Group III and Group V respectively. There was significant reduction in IDRS in Group II (p<0.05); p<0.001 in Group III, Group IV and Group V respectively. Significant difference (p<0.001) in QoL scale and IDRS were found when study groups with standard treatment along with yoga therapy were compared to standard treatment alone.
Yoga therapy along with standard treatment for 12 weeks improved QoL and attenuated the diabetes risk among Indian prediabetics and diabetics compared to standard treatment alone.
印度已成为糖尿病的中心，糖尿病是一种与压力相关的疾病，影响着年轻人群的工作技能和日常生活方式管理。大多数研究报告了瑜伽对改善患有其他合并症的糖尿病患者生活质量（QoL）的作用。迄今为止，尚无随机对照试验报告显示瑜伽疗法对血压正常的糖尿病前期和糖尿病年轻个体的生活质量及印度糖尿病风险评分（IDRS）的影响。
确定为期12周的瑜伽疗法对血压正常的糖尿病前期和糖尿病年轻印度成年人的生活质量及IDRS的影响。
在内分泌科门诊进行了一项随机对照试验。将年龄在18 - 45岁的血压正常参与者（n = 310）分为健康对照组（n = 62）、糖尿病前期患者（n = 124）和糖尿病患者（n = 124）。研究组受试者被随机分配到第二组（n = 62，糖尿病前期 - 标准治疗）、第三组（n = 62，糖尿病前期 - 标准治疗 + 瑜伽疗法）、第四组（n = 62，糖尿病 - 标准治疗）和第五组（n = 62，糖尿病 - 标准治疗 + 瑜伽疗法）。在干预的12周前后评估弗拉纳根生活质量量表、IDRS问卷、空腹血糖（FPG）和胰岛素。使用学生配对t检验和单因素方差分析进行统计分析。
干预前后分析显示，第二组和第四组的生活质量量表有显著改善，p < 0.·01；第三组和第五组分别为p < 0.·001。第二组的IDRS有显著降低（p < 0.·05）；第三组、第四组和第五组分别为p < 0.·001。当将接受标准治疗加瑜伽疗法的研究组与仅接受标准治疗的组进行比较时，发现生活质量量表和IDRS有显著差异（p < 0.·001）。
与单独的标准治疗相比，为期12周的瑜伽疗法联合标准治疗改善了印度糖尿病前期和糖尿病患者的生活质量并降低了糖尿病风险。
