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人脑银行中的生物标志物:神经退行性疾病研究的应用和挑战。

Biovalue in Human Brain Banking: Applications and Challenges for Research in Neurodegenerative Diseases.

机构信息

Department of Neurology and Fixel Institute for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, USA.

出版信息

Methods Mol Biol. 2022;2389:209-220. doi: 10.1007/978-1-0716-1783-0_17.

Abstract

Brain banking occupies a central role for the advancement of the study of human neurodegenerative and neuropsychiatric diseases. The smooth functioning and effectiveness of a brain bank is largely a multidisciplinary effort and requires the cooperation and participation of several players including neurologists, neuropathologists, and research coordinators to guarantee that donated tissue is properly processed and archived. If properly run, brain banks can ultimately lay the foundation for new brain research and pioneer the discovery of new therapies for a variety of neurological diseases.

摘要

脑库在推进人类神经退行性和神经精神疾病的研究方面发挥着核心作用。脑库的顺利运作和有效性在很大程度上是一项多学科的努力,需要神经科医生、神经病理学家和研究协调员等多个参与者的合作和参与,以确保捐赠的组织得到妥善处理和存档。如果管理得当,脑库最终可以为新的大脑研究奠定基础,并为各种神经疾病的新疗法的发现开辟道路。

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