不可逆电穿孔单独及与免疫疗法联合在胰腺癌中的免疫调节作用
Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer.
作者信息
Tian Guo, Guan Jiajia, Chu Yanhua, Zhao Qiyu, Jiang Tian'an
机构信息
Department of Ultrasound Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Biomedicine, Key Laboratory of Pulsed Power Translational Medicine of Zhejiang Province, Hangzhou, China.
出版信息
Front Oncol. 2021 Sep 10;11:712042. doi: 10.3389/fonc.2021.712042. eCollection 2021.
Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment on the immune response of PC remain unknown. Moreover, there are few studies on the therapeutic effect of IRE combining with immunotherapy on PC. Thus, we review recent advances in our understanding of IRE alone and its working with immunotherapy towards the immune response of PC, discussing potential opportunities for exploring future treatment strategies.
新兴研究表明，不可逆电穿孔（IRE）主要针对胰腺癌（PC）。然而，IRE治疗对PC免疫反应的影响尚不清楚。此外，关于IRE联合免疫疗法对PC治疗效果的研究很少。因此，我们回顾了目前对IRE单独及其与免疫疗法协同作用于PC免疫反应的最新认识进展，探讨未来治疗策略的潜在机会。
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