Lenarz T
Infection. 1986;14 Suppl 1:S87-8. doi: 10.1007/BF01645208.
After ascertaining the bacterial spectrum in 105 patients with Otitis media acutissima, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the efficacy of oral therapy with ofloxacin in five patients from each of these groups was assessed. The results are comparable with those following conventional local and intravenous antibiotic therapy. On the basis of these preliminary results, ofloxacin can be considered as a highly efficient oral substance which is effective against Staphylococcus aureus and Pseudomonas aeruginosa, two important pathogens in inflammatory ear infections.
在确定了105例急性化脓性中耳炎、中耳慢性化脓性中耳炎和上鼓室慢性化脓性中耳炎患者的细菌谱后,对每组中的5例患者进行了氧氟沙星口服治疗的疗效评估。结果与传统局部及静脉用抗生素治疗的结果相当。基于这些初步结果,氧氟沙星可被视为一种高效的口服药物,对金黄色葡萄球菌和铜绿假单胞菌有效,这两种是耳部感染炎症中的重要病原体。