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8-12 岁儿童氟斑牙严重程度及其相关因素。

Dental fluorosis severity in children 8-12 years old and associated factors.

机构信息

Universidade Estadual Paulista, São Paulo, Facultad de Odontologia de Araraquara, Programa de Pos-Graduación em Ciências Odontológicas, Araraquara-SP, Brasil.

Universidad CES, Facultad de Odontología, Departamento de investigación, Medellín, Colombia.

出版信息

Acta Odontol Latinoam. 2021 Aug 1;34(2):156-165. doi: 10.54589/aol.34/2/156.

DOI:10.54589/aol.34/2/156
PMID:34570864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10315087/
Abstract

The aim of this study was to determine the frequency and severity of dental fluorosis (DF) and the association between severity and risk factors. In a cross-sectional study, 8- to 12-year-old children, born in a Colombian district, were evaluated according to the Thylstrup and Fejerskov Index (TFI) by two calibrated examiners. Molar Incisor Hypomineralization (MIH) and dental caries (DC) were also evaluated. Ordinal logistic regression was applied (p<0.05). Risk factors and lifestyle factors were collected using a questionnaire answered by parents. DF was detected in 76 (98.7%) of the children (average of 18.4 ±1.81 permanent teeth affected). Grade TF2 was the most frequently observed (34.8%); TF5 was observed in all age groups; TF6- TF7 were observed in 12-year-olds. No association was found between DF severity and DC (Odds Ratio (OR)=1.35; 95%CI: 0.56-3.26) or MIH (OR=1.39; 95%CI: 0.43-4.46). DF severity was significantly associated with use of an indoor wood stove for food preparation (OR = 9.34; 95%CI: 1.11-78.57) and use of a pea-sized volume of toothpaste (OR = 27.42; 95%CI: 1.57-477.36). Prevalence of DC was 38.1% and prevalence of MIH was 14.4%. In this population, the frequency of DF was high and severity was associated with use of an indoor wood stove for food preparation and toothpaste amount used during childhood.

摘要

本研究旨在确定氟斑牙(DF)的频率和严重程度,以及严重程度与危险因素之间的关系。在一项横断面研究中,对出生在哥伦比亚一个区的 8 至 12 岁儿童,根据 Thylstrup 和 Fejerskov 指数(TFI),由两名经过校准的检查者进行评估。还评估了磨牙切牙釉质发育不全(MIH)和龋齿(DC)。应用了有序逻辑回归(p<0.05)。使用家长回答的问卷收集了危险因素和生活方式因素。在 76 名(98.7%)儿童中发现了 DF(平均 18.4 ±1.81 颗恒牙受到影响)。观察到最频繁的 TF2 级(34.8%);TF5 级见于所有年龄组;TF6-TF7 级见于 12 岁儿童。DF 严重程度与 DC(比值比(OR)=1.35;95%CI:0.56-3.26)或 MIH(OR=1.39;95%CI:0.43-4.46)无关。DF 严重程度与使用室内柴火炉进行食物准备(OR=9.34;95%CI:1.11-78.57)和使用豌豆大小的牙膏量(OR=27.42;95%CI:1.57-477.36)显著相关。DC 的患病率为 38.1%,MIH 的患病率为 14.4%。在该人群中,DF 的发病率很高,严重程度与使用室内柴火炉进行食物准备和儿童时期使用的牙膏量有关。

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Indian J Dent Res. 2019 May-Jun;30(3):462-467. doi: 10.4103/ijdr.IJDR_498_17.
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The association between the prevalence of dental fluorosis and the socio-economic status and area of residence of 12-year-old students in Uruguay.乌拉圭 12 岁学生氟斑牙患病率与社会经济地位和居住地的关系。
Acta Odontol Scand. 2020 Jan;78(1):26-30. doi: 10.1080/00016357.2019.1642514. Epub 2019 Jul 22.
3
Dental Fluorosis Trends in US Oral Health Surveys: 1986 to 2012.
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Clin Oral Investig. 2025 Jun 2;29(6):327. doi: 10.1007/s00784-025-06411-4.
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Correlation between dental fluorosis risk and bone-specific alkaline phosphatase, osteocalcin, matrix metalloproteinase and parathyroid hormone in children.儿童牙氟中毒风险与骨特异性碱性磷酸酶、骨钙素、基质金属蛋白酶及甲状旁腺激素之间的相关性
J Med Biochem. 2024 Nov 16;43(6):890-896. doi: 10.5937/jomb0-48581.
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PLoS One. 2024 Sep 16;19(9):e0310420. doi: 10.1371/journal.pone.0310420. eCollection 2024.
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Cochrane Database Syst Rev. 2024 Jun 20;6(6):CD007693. doi: 10.1002/14651858.CD007693.pub3.
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