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感染和胃外疾病-以中枢神经系统为重点。

Infection and Extragastric Diseases-A Focus on the Central Nervous System.

机构信息

Chair and Department of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.

Department of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.

出版信息

Cells. 2021 Aug 25;10(9):2191. doi: 10.3390/cells10092191.

Abstract

() is most known to cause a wide spectrum of gastrointestinal impairments; however, an increasing number of studies indicates that infection might be involved in numerous extragastric diseases such as neurological, dermatological, hematologic, ocular, cardiovascular, metabolic, hepatobiliary, or even allergic diseases. In this review, we focused on the nervous system and aimed to summarize the findings regarding infection and its involvement in the induction/progression of neurological disorders. Neurological impairments induced by infection are primarily due to impairments in the gut-brain axis (GBA) and to an altered gut microbiota facilitated by colonization. Currently, regarding a potential relationship between infection and neurological disorders, most of the studies are mainly focused on .

摘要

幽门螺杆菌最常引起广泛的胃肠道损伤;然而,越来越多的研究表明,感染可能与许多胃外疾病有关,如神经、皮肤、血液、眼睛、心血管、代谢、肝胆,甚至过敏疾病。在这篇综述中,我们专注于神经系统,并旨在总结关于感染及其在诱导/进展神经障碍中的作用的发现。感染引起的神经损伤主要是由于肠道-大脑轴(GBA)的损伤和 定植引起的肠道微生物群改变。目前,关于感染和神经障碍之间的潜在关系,大多数研究主要集中在。

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