Ju Ying-Tzu, Wei Yu-Jen, Hsieh Ming-Ling, Wang Jieh-Neng, Wu Jing-Ming
Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.
Children (Basel). 2021 Sep 9;8(9):790. doi: 10.3390/children8090790.
Congenital complete heart block is defined as a complete atrioventricular block occurring prenatally, at birth, or within the first month of life. Congenital complete heart block has a high mortality rate, and in infants with normal heart morphology, it is often associated with maternal connective tissue disease. In these latter cases, neonatal congenital complete heart block is usually irreversible. We present a rare case of a female neonate who had bradycardia noted at a gestational age of 37 weeks. Her mother had no autoimmune disease history. She had no structural heart disease, and the serology surveys for autoantibodies including SSA/Ro and SSB/La were all negative. Without intervention or medication, her congenital complete heart block completely recovered to a normal sinus rhythm within 5 days. The cause of the transient congenital complete heart block was unknown in this case.
先天性完全性心脏传导阻滞被定义为产前、出生时或出生后第一个月内发生的完全性房室传导阻滞。先天性完全性心脏传导阻滞死亡率很高，在心脏形态正常的婴儿中，它常与母体结缔组织病有关。在这些病例中，新生儿先天性完全性心脏传导阻滞通常是不可逆的。我们报告一例罕见的女性新生儿病例，该患儿在孕37周时被发现有心动过缓。其母亲无自身免疫性疾病史。患儿无结构性心脏病，包括抗SSA/Ro和抗SSB/La等自身抗体的血清学检查均为阴性。未经干预或药物治疗，其先天性完全性心脏传导阻滞在5天内完全恢复为正常窦性心律。该病例中短暂性先天性完全性心脏传导阻滞的病因不明。
