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一名新生儿出现短暂性心脏传导阻滞,与先前未诊断出的母体抗Ro/SSA和抗La/SSB抗体有关。

Transient heart block in a neonate associated with previously undiagnosed maternal anti-Ro/SSA and anti-La/SSB antibodies.

作者信息

Escamilla S A, Pettersen M D

机构信息

Pediatric Cardiology at Children's Hospital of Michigan, Detroit, MI 48201, USA.

出版信息

Pediatr Cardiol. 2007 May-Jun;28(3):221-3. doi: 10.1007/s00246-006-0015-2. Epub 2007 Mar 20.

Abstract

This report presents the case of an infant who was born with transient complete heart block. The cardiac rhythm converted to normal sinus rhythm within 12 hours of life. Following the diagnosis in this infant of congenital heart block, both the mother and the infant were tested for autoantibodies. Both were found to be strongly positive for anti-Ro/SSA antibodies. The infant was also weakly positive for the anti-La/SSB antibodies and her mother moderately positive for the same. Congenital heart block associated with these maternal antibodies is well documented in the literature; however, this is the only reported case that documents a transient nature of the complete heart block.

摘要

本报告介绍了一名出生时患有暂时性完全性心脏传导阻滞的婴儿病例。该婴儿的心律在出生后12小时内转为正常窦性心律。在诊断出该婴儿患有先天性心脏传导阻滞后,对母亲和婴儿都进行了自身抗体检测。结果发现两人的抗Ro/SSA抗体均呈强阳性。婴儿的抗La/SSB抗体呈弱阳性,其母亲的该抗体呈中度阳性。文献中已充分记载了与这些母体抗体相关的先天性心脏传导阻滞;然而,这是唯一一例记录了完全性心脏传导阻滞具有暂时性的报告病例。

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