N Deepa, Achar Premila N, Sreenivasa Marikunte Y
Department of Studies in Microbiology, University of Mysore, Mysuru 570 006, Karnataka, India.
Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, GA 30144, USA.
J Fungi (Basel). 2021 Sep 18;7(9):776. doi: 10.3390/jof7090776.
is the most predominant fungal phytopathogen of cereals and it is posing great concern from a global perspective. The fungus is mainly associated with maize, rice, sorghum, wheat, sugarcane, banana, and asparagus and causes cob, stalk, ear, root, crown, top, and foot rot. produces fumonisins as the major secondary metabolite along with trace levels of beauvericin, fusaric acid, fusarin C, gibberiliformin, and moniliformin. Being a potential carcinogen, fumonisins continue to receive major attention as they are common contaminants in cereals and its processed food products. The importance of elimination of growth and its associated fumonisin from cereals cannot be overemphasized considering the significant health hazards associated with its consumption. Physical and chemical approaches have been shown to reduce fumonisin B1 concentrations among feeds and food products but have proved to be ineffective during the production process. Hence, biological control methods using microorganisms, plant extracts, antioxidants, essential oils, phenolic compounds, and other advanced technologies such as growing disease-resistant crops by applying genetic engineering, have become an effective alternative for managing and its toxin. The different methods, challenges, and concerns regarding the biocontrol of and production of fumonisin B1 have been addressed in the present review.
是谷物中最主要的真菌植物病原体,从全球角度来看,它引起了极大关注。这种真菌主要与玉米、水稻、高粱、小麦、甘蔗、香蕉和芦笋有关,会导致玉米棒、茎、穗、根、冠、顶部和根部腐烂。它产生伏马菌素作为主要的次生代谢产物,同时还有微量的白僵菌素、镰刀菌酸、镰刀菌素C、赤霉烯醇和串珠镰刀菌素。作为一种潜在的致癌物,伏马菌素一直备受关注,因为它们是谷物及其加工食品中的常见污染物。考虑到食用谷物及其相关伏马菌素会带来重大健康危害,消除谷物中该真菌的生长及其相关伏马菌素的重要性再怎么强调也不为过。物理和化学方法已被证明可降低饲料和食品中伏马菌素B1的浓度,但在生产过程中已证明无效。因此,使用微生物、植物提取物、抗氧化剂、精油、酚类化合物的生物防治方法,以及其他先进技术,如通过基因工程培育抗病作物,已成为管理该真菌及其毒素的有效替代方法。本综述探讨了有关该真菌生物防治和伏马菌素B1产生的不同方法、挑战和问题。