Shrivastava Deepti, Natoli Valentino, Srivastava Kumar Chandan, Alzoubi Ibrahim A, Nagy Ahmed Ismail, Hamza May Othman, Al-Johani Khalid, Alam Mohammad Khursheed, Khurshid Zohaib
Periodontics, Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.
Department of Dentistry, School of Biomedical and Health Sciences, European University of Madrid, 28670 Madrid, Spain.
Microorganisms. 2021 Sep 16;9(9):1966. doi: 10.3390/microorganisms9091966.
Dental biofilm plays a very crucial role in the etiopathogenesis of periodontal andperi-implant diseases. Over the past decade, tremendous research has been carried outto know the structure of biofilm and the mechanism by which it causes the destruction of supporting tissues of tooth or implant. Periodontal or peri-implant therapy usually begins with primarily removing thebiofilm and is considered as non-surgical mechanical debridement. Although scaling and root planing (SRP) is regarded as a gold standard for mechanical plaque debridement, various other means of biofilm removal have constantly been evolving. These may vary from different scaling systems such as vector systems to decontamination of pockets with LASER therapy. Nowadays, a new concept has emerged known as "guided biofilm therapy" (GBT). It is beneficial in removing the biofilm around the tooth and implant structures, resulting in better or comparable clinical outcomes than SRP. These results were substantiated with the reduction in the microbial load as well as the reduction in the inflammatory cytokines. This review will highlight the various aspects of GBT used in periodontal and peri-implant disease.
牙菌斑生物膜在牙周病和种植体周围疾病的病因发病机制中起着至关重要的作用。在过去十年中，人们进行了大量研究以了解生物膜的结构及其导致牙齿或种植体支持组织破坏的机制。牙周或种植体周围治疗通常首先从去除生物膜开始，这被视为非手术机械清创术。尽管龈上洁治和根面平整（SRP）被视为机械性菌斑清除的金标准，但其他各种去除生物膜的方法也在不断发展。这些方法可能从不同的洁治系统（如超声系统）到激光治疗牙周袋去污不等。如今，出现了一个新的概念，即“引导性生物膜治疗”（GBT）。它有助于去除牙齿和种植体结构周围的生物膜，产生比SRP更好或相当的临床效果。这些结果通过微生物负荷的降低以及炎症细胞因子的减少得到了证实。本综述将重点介绍GBT在牙周病和种植体周围疾病中的各个方面。
