Vejendla Ipsitha, Krithikadatta Jogikalmat, Vinothkumar Thilla Sekar, Chandan Srivastava Kumar, Mohammad Dhuwayhi Alruwaili Balqees, Saleh Aljarid Manal Yahya, Shrivastava Deepti
Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, Tamil Nadu, India.
Department of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, Tamil Nadu, India.
Scientifica (Cairo). 2025 May 29;2025:9344221. doi: 10.1155/sci5/9344221. eCollection 2025.
The systematic review aim was to assess the antibiofilm properties of miswak () in comparison with conventional oral health measures in the adult population. A comprehensive search strategy was formed, and electronic databases (Scopus, PubMed, Web of Science, ProQuest, and Cochrane Library), gray literature, and clinical trials registry (clinicaltrials.gov) were searched to identify the relevant articles. The inclusion criteria were based on the PICOS strategy. Randomized controlled trials (RCTs) involving the adult population comparing the use of miswak with conventional oral health measures were included in the review. Adult populations undergoing orthodontic treatment and other study designs were excluded. The included studies were assessed for qualitative analysis, and the data extraction was done by two independent reviewers. The outcome of the review was to compare the antibiofilm activity of miswak and conventional oral hygiene measures. The risk of bias in these research studies has been determined based on the guidelines of the Cochrane Handbook for Systematic Reviews of Interventions. Out of 474 identified articles, 10 studies have been included for qualitative analysis, based on eligibility criteria, with a total of 442 individuals. These studies, published between 2011 and 2023, primarily focused on assessing the antiplaque efficacy of miswak and its effectiveness in reducing cariogenic bacterial load. Miswak exhibited positive effects in antibacterial and antiplaque activity, showing the potential to reduce plaque accumulation and gingival inflammation. When is used to maintain dental hygiene, there is a noteworthy decrease in the amount of cariogenic bacteria and plaque. To evaluate the benefits and appropriate outcomes of miswak practice in terms of maintaining dental health, more clinical research is advised.
本系统评价的目的是评估在成年人群中，与传统口腔卫生措施相比，牙刷草（）的抗生物膜特性。制定了全面的检索策略，并检索了电子数据库（Scopus、PubMed、Web of Science、ProQuest和Cochrane图书馆）、灰色文献和临床试验注册库（clinicaltrials.gov）以识别相关文章。纳入标准基于PICOS策略。本评价纳入了涉及成年人群、比较使用牙刷草与传统口腔卫生措施的随机对照试验（RCT）。接受正畸治疗的成年人群和其他研究设计被排除。对纳入的研究进行定性分析评估，数据提取由两名独立的评审员完成。评价的结果是比较牙刷草和传统口腔卫生措施的抗生物膜活性。这些研究的偏倚风险已根据《Cochrane干预措施系统评价手册》的指南确定。在474篇已识别的文章中，根据纳入标准，有10项研究被纳入定性分析，共442人。这些研究发表于2011年至2023年之间，主要侧重于评估牙刷草的抗牙菌斑功效及其在降低致龋菌负荷方面的有效性。牙刷草在抗菌和抗牙菌斑活性方面表现出积极作用，显示出减少牙菌斑积聚和牙龈炎症的潜力。当使用牙刷草保持口腔卫生时，致龋菌和牙菌斑的数量有显著减少。为了评估使用牙刷草在保持口腔健康方面的益处和适当结果，建议进行更多的临床研究。
