Alashrah Saleh, El-Ghoul Yassine, Almutairi Faisal Muteb, Omer Mohammed Ahmed Ali
Department of Physics, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.
Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.
Polymers (Basel). 2021 Sep 17;13(18):3140. doi: 10.3390/polym13183140.
Currently, the uncontrolled exposure of individuals to X-rays during medical examinations represents a substantial danger that threatens both medical professionals and patients. Therefore, radiation dosimetry for low X-ray doses is a very important control of radiation practice in medical diagnostic radiology. In line with this, the current study proposes a valuable dosimeter-based PVA thin film doubly doped with silver nitrate salt and nitro blue tetrazolium dye. The nanocomposite film was prepared via a simple casting method and the different processing parameters were optimized. The performance of radiation detection was evaluated according to optical, chromic, chemical and structural changes after exposure to variable low X-ray doses (0, 2, 4, 10 and 20 mGy). The different film labels exhibited an excellent stability behavior in dark and light upon 30 days of storage. The UV-Vis spectrophotometric study showed a gradual increase in the maximum absorbance as a function of the dose and the corresponding response curve confirmed this linear variation (R = 0.998). A clear structural modification was recorded via X-ray diffraction (XRD) analysis revealing the increase in crystallinity with the level of the dose received by the nanocomposite films. Microscopic surface analysis via SEM assessments revealed a significant morphological change in PVA/Ag/NBT films exposed to increased radiation doses and typical dendrites growing in needle- or tree-like microstructures appeared with a high X-ray dose. Finally, the nanocomposite films before and after irradiation were evaluated via a spectrocolorimetric study and the different CIELab coordinates, the color difference, as well as the color strength, showed a linear correlation with the intensity of the applied dose. This new dosimeter design could, therefore, provide a promising and efficient alternative for prompt and accurate detection of low X-rays doses in diagnostic radiology.
目前，在医学检查过程中个人不受控制地暴露于X射线下，对医学专业人员和患者都构成了重大威胁。因此，低剂量X射线的辐射剂量测定是医学诊断放射学中辐射实践的一项非常重要的控制措施。与此一致，当前的研究提出了一种有价值的基于剂量计的聚乙烯醇（PVA）薄膜，该薄膜同时掺杂了硝酸银盐和硝基蓝四氮唑染料。通过简单的浇铸方法制备了纳米复合薄膜，并对不同的加工参数进行了优化。根据在暴露于可变低剂量X射线（0、2、4、10和20毫戈瑞）后光学、变色、化学和结构的变化，评估了辐射检测性能。在储存30天期间，不同的薄膜标签在黑暗和光照条件下均表现出优异的稳定性。紫外可见分光光度研究表明，最大吸光度随剂量增加而逐渐增大，相应的响应曲线证实了这种线性变化（R = 0.998）。通过X射线衍射（XRD）分析记录到明显的结构变化，表明纳米复合薄膜的结晶度随所接受剂量水平的增加而提高。通过扫描电子显微镜（SEM）评估进行的微观表面分析显示，暴露于增加的辐射剂量下的PVA/Ag/NBT薄膜出现了显著的形态变化，在高X射线剂量下出现了典型的针状或树状微观结构中生长的枝晶。最后，通过分光比色研究评估了辐照前后的纳米复合薄膜，不同的CIELab坐标、色差以及色强度与所施加剂量的强度呈线性相关。因此，这种新的剂量计设计可为诊断放射学中快速准确地检测低剂量X射线提供一种有前景且高效的替代方案。
