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严重 COVID-19 后终末期呼吸衰竭的肺移植：2 例报告。

Lung Transplantation for End-Stage Respiratory Failure After Severe COVID-19: A Report of 2 Cases.

机构信息

Department of Thoracic Surgery, University Medical Center, Ljubljana, Slovenia.

Department of Pulmonary Diseases and Allergy, University Medical Center, Ljubljana, Slovenia; Medical Faculty, University of Ljubljana, Slovenia.

出版信息

Transplant Proc. 2021 Oct;53(8):2495-2497. doi: 10.1016/j.transproceed.2021.08.029. Epub 2021 Aug 28.

DOI:10.1016/j.transproceed.2021.08.029
PMID:34579953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8397535/
Abstract

We report 2 cases of bilateral lung transplantation for nonresolving coronavirus disease 2019 associated respiratory failure. In the first patient, the severe acute respiratory syndrome coronavirus 2 infection caused acute respiratory distress syndrome requiring prolonged extracorporeal membrane oxygenation support; in the second patient, coronavirus disease 2019 resulted in irreversible pulmonary fibrosis requiring only ventilatory support. The 2 cases represent the 2 ends of the spectrum showing significant differences in preoperative and postoperative courses.

摘要

我们报告了 2 例因持续的 2019 冠状病毒病相关呼吸衰竭而行双侧肺移植的病例。在第 1 例患者中，严重急性呼吸综合征冠状病毒 2 感染导致急性呼吸窘迫综合征，需要长时间的体外膜氧合支持；在第 2 例患者中，2019 冠状病毒病导致不可逆的肺纤维化，仅需通气支持。这 2 例病例代表了疾病谱的两端，在术前和术后的病程中存在显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/bdf4afe762b1/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/5c5724b3dc6b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/bc09c8098ac9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/bdf4afe762b1/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/5c5724b3dc6b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/bc09c8098ac9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7835/8397535/bdf4afe762b1/gr3_lrg.jpg

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本文引用的文献

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Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries.COVID-19 肺移植术后早期结局：来自四个国家的一系列首例连续病例。
Lancet Respir Med. 2021 May;9(5):487-497. doi: 10.1016/S2213-2600(21)00077-1. Epub 2021 Mar 31.
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Lung Transplantation for Severe Post-coronavirus Disease 2019 Respiratory Failure.严重新型冠状病毒病 2019 后呼吸衰竭的肺移植。
Transplantation. 2021 Jun 1;105(6):1381-1387. doi: 10.1097/TP.0000000000003706.
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Lung transplantation for patients with severe COVID-19.
COVID-19 在实体器官移植中的概述。
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肺移植治疗重症 COVID-19 患者。
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When to consider lung transplantation for COVID-19.何时考虑对COVID-19患者进行肺移植。
Lancet Respir Med. 2020 Oct;8(10):944-946. doi: 10.1016/S2213-2600(20)30393-3. Epub 2020 Aug 25.
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Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient.对一名PCR检测呈阳性的新冠病毒肺炎相关急性呼吸窘迫综合征患者进行肺移植
Lancet Respir Med. 2020 Oct;8(10):1057-1060. doi: 10.1016/S2213-2600(20)30361-1. Epub 2020 Aug 25.
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Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study.体外膜肺氧合治疗 COVID-19 相关严重急性呼吸窘迫综合征的回顾性队列研究。
Lancet Respir Med. 2020 Nov;8(11):1121-1131. doi: 10.1016/S2213-2600(20)30328-3. Epub 2020 Aug 13.
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Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.意大利伦巴第地区重症监护病房中 COVID-19 患者死亡的相关危险因素。
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