Neefjes J J, Hensen E J, de Kroon T I, Ploegh H L
Immunogenetics. 1986;23(5):341-7. doi: 10.1007/BF00398799.
The polymorphism of feline MHC antigens was examined using biochemical methods. The following observations were made: (1) feline class I and II antigens are polymorphic. Their biochemical features were established using rabbit and mouse reagents directed against human MHC products; they resemble those observed for other mammalian species; (2) the expression of class II antigens in unstimulated cat peripheral blood lymphocytes (PBLs) appears to be unusually high. Cat PBLs express far more class II than class I antigens, whereas in human Epstein-Barr virus-transformed lines, which are known to express relatively large amounts of class II antigens, the situation is reversed.
利用生化方法检测了猫主要组织相容性复合体（MHC）抗原的多态性。得到了以下观察结果：（1）猫的Ⅰ类和Ⅱ类抗原具有多态性。利用针对人类MHC产物的兔和鼠试剂确定了它们的生化特征；这些特征与在其他哺乳动物物种中观察到的相似；（2）未受刺激的猫外周血淋巴细胞（PBL）中Ⅱ类抗原的表达似乎异常高。猫PBL表达的Ⅱ类抗原远比Ⅰ类抗原多，而在已知表达相对大量Ⅱ类抗原的人Epstein-Barr病毒转化系中，情况则相反。
