School of Public Health, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Department of Pediatric, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 611731, People's Republic of China.
Syst Rev. 2021 Sep 30;10(1):262. doi: 10.1186/s13643-021-01805-3.
To analyze the effectiveness and quality of stroke clinical practice guidelines (CPGs) published in recent years in order to guide future guideline developers to develop better guidelines.
No patient involved METHOD: PubMed, China Biology Medicine (CBM), Wanfang, CNKI, and CPG-relevant websites were searched from January 2015 to December 2019 by two researchers independently. The RIGHT (Reporting Items for Practice Guidelines in Healthcare) checklist was used to assess the reporting quality in terms of domains and items. Then, a subgroup analysis of the results was performed.
RIGHT checklist reporting rate RESULTS: A total of 66 CPGs were included. Twice as many CPGs were published internationally as were published in China. More than half were updated. Most CPGs are published in journals, developed by societies or associations, and were evidence-based grading. The average reporting rate for all included CPGs was 47.6%. Basic information got the highest (71.7% ± 19.7%) reporting rate, while review and quality assurance got the lowest (22.0% ± 24.6%). Then, a cluster analysis between countries, publishing channels, and institutions was performed. There were no statistically significant differences in the reporting quality on the CPGs between publishing countries (China vs. international), publishing channels (journals vs. websites), and institutions (associations vs. non-associations).
Current stroke CPGs reports are of low quality. We recommend that guideline developers improve the quality of reporting of key information and improve the management of conflicts of interest. We recommend that guideline developers consider the RIGHT checklist as an important tool for guideline development.
分析近年来发表的脑卒中临床实践指南（CPG）的有效性和质量，以指导未来指南制定者制定更好的指南。
无患者参与
研究者 2 名独立检索 2015 年 1 月至 2019 年 12 月的 PubMed、中国生物医学文献数据库（CBM）、万方、中国知网（CNKI）和 CPG 相关网站。采用 RIGHT（医疗保健实践指南报告项目）清单评估各领域和项目的报告质量。然后，对结果进行了亚组分析。
RIGHT 清单报告率
共纳入 66 项 CPG。国际发表的 CPG 是中国发表的两倍。超过一半的 CPG 是更新的。大多数 CPG 发表在期刊上，由学会或协会制定，并进行了证据分级。所有纳入 CPG 的平均报告率为 47.6%。基本信息的报告率最高（71.7%±19.7%），而审查和质量保证的报告率最低（22.0%±24.6%）。然后，对国家、出版渠道和机构之间进行了聚类分析。在 CPG 出版国家（中国与国际）、出版渠道（期刊与网站）和机构（协会与非协会）之间，报告质量没有统计学差异。
目前脑卒中 CPG 的报告质量较低。我们建议指南制定者提高关键信息报告的质量，并加强利益冲突的管理。我们建议指南制定者将 RIGHT 清单作为指南制定的重要工具。
