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由[具体病因未提及]引起的布鲁氏菌病疫情——中国陕西省泾阳县,2020年3月至5月

Brucellosis Outbreak Caused by - Jingyang County, Shaanxi Province, China, March-May, 2020.

作者信息

Chang Wenhui, Sun Yangxin, Fan Suoping, An Cuihong, Nie Shoumin, Tian Guozhong, Luo Boyan, Yang Hongxun, Zhai Xiaohua, Tian Haiying, Zhang Jia, Jiang Hai

机构信息

Shaanxi Provincial Centre for Disease Control and Prevention, Xian, Shaanxi, China.

State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

出版信息

China CDC Wkly. 2020 Sep 25;2(39):753-756. doi: 10.46234/ccdcw2020.204.

DOI:10.46234/ccdcw2020.204
PMID:34594754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8393012/
Abstract

Brucellosis is one of the world's most overlooked zoonotic diseases, and humans can easily acquire brucellosis from animals and their products. Reemerging brucellosis outbreaks are probably attributable to sociocultural factors and compounded by the lack of adequate control measures in sheep and goat rearing systems. This is the first identified outbreak caused by bv.3 in Jingyang County, Xianyang City, Shaanxi Province. A total of 13 seropositve cases (7 acute patients and 6 asymptomatic persons) were identified from March to May, 2020, and the investigation indicated that sheep-to-canine-to-human was the likely transmission route. Effective control of sheep brucellosis will significantly reduce the risk of human brucellosis. Priority should be given to building cooperation between all stakeholders, maintaining epidemiological surveillance to detect human brucellosis at medical centers, and making case reporting mandatory for both veterinary and public health services.

摘要

布鲁氏菌病是世界上最被忽视的人畜共患病之一,人类很容易从动物及其产品中感染布鲁氏菌病。布鲁氏菌病疫情的再次出现可能归因于社会文化因素,而绵羊和山羊养殖系统缺乏适当的控制措施又使情况更加复杂。这是陕西省咸阳市泾阳县首次发现由3型生物变种引起的疫情。2020年3月至5月共确诊13例血清学阳性病例(7例急性患者和6例无症状感染者),调查表明羊传犬再传人可能是传播途径。有效控制绵羊布鲁氏菌病将显著降低人类感染布鲁氏菌病的风险。应优先建立所有利益相关者之间的合作,维持流行病学监测以在医疗中心发现人类布鲁氏菌病病例,并强制兽医和公共卫生服务部门进行病例报告。

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引用本文的文献

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Multiple lineages are driving the human brucellosis epidemic in Shaanxi Province, China: evidence from whole genome sequencing-based analysis.多种谱系导致中国陕西省人间布鲁氏菌病流行:基于全基因组测序分析的证据。
Front Cell Infect Microbiol. 2024 Oct 30;14:1452143. doi: 10.3389/fcimb.2024.1452143. eCollection 2024.

本文引用的文献

1
Whole genome sequencing of Brucella melitensis isolated from 57 patients in Germany reveals high diversity in strains from Middle East.对从德国57名患者身上分离出的羊种布鲁氏菌进行全基因组测序,结果显示来自中东的菌株具有高度多样性。
PLoS One. 2017 Apr 7;12(4):e0175425. doi: 10.1371/journal.pone.0175425. eCollection 2017.
2
Full genome SNP-based phylogenetic analysis reveals the origin and global spread of Brucella melitensis.基于全基因组单核苷酸多态性的系统发育分析揭示了羊种布鲁氏菌的起源和全球传播情况。
BMC Genomics. 2015 Feb 18;16(1):93. doi: 10.1186/s12864-015-1294-x.
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Monitoring infected dogs after a canine brucellosis outbreak.布鲁氏菌病疫情后对感染犬进行监测。
Comp Immunol Microbiol Infect Dis. 2012 Dec;35(6):533-7. doi: 10.1016/j.cimid.2012.05.004. Epub 2012 Jun 25.
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MLVA genotyping of Chinese human Brucella melitensis biovar 1, 2 and 3 isolates.中国羊种布鲁氏菌 1、2、3 型分离株的 MLVA 基因分型。
BMC Microbiol. 2011 Nov 22;11:256. doi: 10.1186/1471-2180-11-256.
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Brucellosis in Venezuela.委内瑞拉的布鲁氏菌病。
Vet Microbiol. 2002 Dec 20;90(1-4):39-44. doi: 10.1016/s0378-1135(02)00243-2.