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2022年中国山东省威海市一起人间布鲁氏菌病疫情的分子流行病学研究

Molecular Epidemiological Study of a Human Brucellosis Outbreak - Weihai City, Shandong Province, China, 2022.

作者信息

Li Yan, Yu Yifan, Zhao Jian, Ding Shujun, Zhang Guoying, Yu Xiaolin, Kou Zengqiang

机构信息

Shandong Provincial Center for Disease Control and Prevention, Jinan City, Shandong Province, China.

Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan City, Shandong Province, China.

出版信息

China CDC Wkly. 2024 Mar 22;6(12):230-234. doi: 10.46234/ccdcw2024.046.

DOI:10.46234/ccdcw2024.046
PMID:38633432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11018512/
Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Brucellosis, mainly caused by (), is regarded as a significant zoonotic disease in China. In Weihai, located at the eastern end of the Shandong Peninsula, brucellosis has been in a low epidemic phase for the past five years.

WHAT IS ADDED BY THIS REPORT?: This was the initial report of a brucellosis outbreak in the last five years. Strains of bv. 3 from Weihai and other cities showed a close genetic relationship, suggesting a potential common ancestry.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Epidemiological investigations depend on standardized and effective molecular typing methods and analysis tools for public health laboratories to identify and trace outbreaks. Understanding the circulation patterns of livestock in free-range households in heavily affected areas is essential for controlling the spread of brucellosis.

摘要

关于该主题已知的信息有哪些?:布鲁氏菌病主要由()引起,在中国被视为一种重要的人畜共患病。位于山东半岛东端的威海,在过去五年中布鲁氏菌病一直处于低流行阶段。

本报告新增了哪些内容?:这是过去五年中布鲁氏菌病疫情爆发的首次报告。来自威海及其他城市的3型布鲁氏菌菌株显示出密切的遗传关系,表明可能有共同的祖先。

对公共卫生实践有哪些启示?:流行病学调查依赖于标准化且有效的分子分型方法以及分析工具,供公共卫生实验室识别和追踪疫情爆发。了解受严重影响地区散养户家畜的流通模式对于控制布鲁氏菌病的传播至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f165/11018512/33278f50cab1/ccdcw-6-12-230-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f165/11018512/c3421ae31a5d/ccdcw-6-12-230-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f165/11018512/33278f50cab1/ccdcw-6-12-230-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f165/11018512/c3421ae31a5d/ccdcw-6-12-230-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f165/11018512/33278f50cab1/ccdcw-6-12-230-2.jpg

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