Department of Internal Medicine, University Hospitals Leuven, Leuven, Belgium.
Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.
Acta Gastroenterol Belg. 2021 Jul-Sep;84(3):401-405. doi: 10.51821/84.3.003.
A prospective registration of patients with colorectal cancer and a colonoscopy within the last 10 years. We tried to classify these post-colonoscopy colorectal cancers (PCCRCs) by most reasonable explanation and into subcategories suggested by the World Endoscopy Organization (WEO) and calculated the unadjusted PCCRC rate.
47 PCCRCs were identified. The average age at diagnosis of PCCRC was 73 years. PCCRCs were more located in the right colon with a higher percentage of MSI-positive and B-RAF mutated tumours. The average period between index colonoscopy and diagnosis of PCCRC was 4.2 years. Sixty-eight % of all PCCRCs could be explained by procedural factors. The mean PCCRC-3y of our department was 2.46%.
The data of our centre are in line with the data of the literature from which can be concluded that most postcolonoscopy colorectal cancers are preventable. The PCCRC-3y is an important quality measure for screening colonoscopy. Ideally all centres involved in the population screening should measure the PCCRC-3 y annually, with cooperation of the cancer registry and reimbursement data provided by the Intermutualistic Agency (IMA).
前瞻性登记最近 10 年内患有结直肠癌并接受结肠镜检查的患者。我们试图通过最合理的解释对这些结肠镜检查后的结直肠癌（PCCRC）进行分类，并归入世界内镜组织（WEO）提出的亚类，计算未经调整的 PCCRC 发生率。
共发现 47 例 PCCRC。PCCRC 的诊断平均年龄为 73 岁。PCCRC 更多位于右半结肠，MSI 阳性和 B-RAF 突变肿瘤的比例更高。指数结肠镜检查与 PCCRC 诊断之间的平均时间为 4.2 年。68%的所有 PCCRC 可归因于程序因素。我们科室的平均 PCCRC-3y 为 2.46%。
我们中心的数据与文献数据一致，可得出结论，大多数结肠镜检查后的结直肠癌是可以预防的。PCCRC-3y 是筛查结肠镜检查的重要质量指标。理想情况下，所有参与人群筛查的中心都应每年测量 PCCRC-3y，与癌症登记处合作，并由互保机构（IMA）提供报销数据。
