Institute of Grain Quality and Nutrition Research, Academy of National Food and Strategic Reserves Administration, Beijing, 100037, People's Republic of China.
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, People's Republic of China.
Nutr J. 2021 Oct 3;20(1):83. doi: 10.1186/s12937-021-00739-9.
A growing number of researches supported that dietary fructose was associated with most of the key features of metabolic syndrome (MetS). However, there was no related epidemiological studies among Chinese population, despite the sharp increase in MetS cases. This study explores the relationship between dietary fructose and MetS among Chinese residents aged 45 and above.
A total of 25,528 participants (11,574 males and 13,954 females) were included in this nationwide representative cross-sectional study of China National Nutrition and Health Survey. Dietary fructose intake was assessed by 3-day 24-h dietary records. MetS was defined by the International Diabetes Federation and Chinese Diabetes Society criteria.
The consumption of dietary fructose was 11.6 g/day for urban residents and 7.6 g/day for rural residents. Fruits and vegetables as well as their products were the main sources of fructose intake. There was no association between dietary fructose intake and the odds of having MetS in both urban (P = 0.315) and rural residents (P = 0.230) after adjustment for confounding factors. Moreover, for urban residents participating physical activities, the odds of having MetS in the fourth quartiles (OR: 0.67; 95%CI: 0.52-0.87) was lower than that in the first quartile. In the sensitivity analysis, a significant reduction in the odds of having MetS was also found in the fourth quartiles (OR, 95%CI: 0.68, 0.51-0.90; 0.67, 0.49-0.91; 0.74, 0.56-0.99) compared with the first quartile when excluding smokers, alcohol users, and underweight/obesity, respectively. And there was no association between dietary fructose intake and the odds of having MetS after multivariate adjustment stratified by gender, smoking and alcohol use.
Under the current dietary fructose intake status, there was no association between dietary fructose intake and the odds of having MetS among Chinese residents aged 45 and above. Physical activity and relatively low fructose intake may have a beneficial synergistic effect on MetS.
越来越多的研究支持膳食果糖与代谢综合征（MetS）的大多数关键特征有关。然而，尽管 MetS 病例急剧增加，但中国人群中却没有相关的流行病学研究。本研究旨在探讨中国 45 岁及以上居民膳食果糖与 MetS 的关系。
本研究采用全国代表性的中国居民营养与健康状况调查的横断面研究，共纳入 25528 名参与者（男性 11574 名，女性 13954 名）。膳食果糖摄入量通过 3 天 24 小时膳食记录进行评估。MetS 按照国际糖尿病联盟和中华糖尿病学会的标准进行定义。
城市居民的膳食果糖摄入量为 11.6 g/天，农村居民为 7.6 g/天。水果、蔬菜及其制品是果糖摄入的主要来源。调整混杂因素后，城市（P=0.315）和农村（P=0.230）居民的膳食果糖摄入量与 MetS 发生的比值比（OR）均无统计学关联。此外，对于参加体力活动的城市居民，第 4 四分位数（OR：0.67；95%CI：0.52-0.87）发生 MetS 的比值比低于第 1 四分位数。在敏感性分析中，当分别排除吸烟者、饮酒者和体重不足/超重者后，第 4 四分位数（OR，95%CI：0.68，0.51-0.90；0.67，0.49-0.91；0.74，0.56-0.99）与第 1 四分位数相比，MetS 的比值比也显著降低。经性别、吸烟和饮酒情况的多变量调整后，膳食果糖摄入量与 MetS 发生的比值比之间也无关联。
在当前的膳食果糖摄入量水平下，中国 45 岁及以上居民的膳食果糖摄入量与 MetS 发生的比值比无关联。体力活动和相对较低的果糖摄入量可能对 MetS 具有有益的协同作用。
Zotero 插件