IgM类风湿因子阴性侵蚀性慢性多关节炎（c.p.）患者的免疫遗传学研究
[Immunogenetic studies in patients with IgM rheumatoid factor negative erosive chronic polyarthritis (c.p.)].
作者信息
Bröll H, Haberhauer G
出版信息
Z Rheumatol. 1986 Mar-Apr;45(2):57-9.
PMID:3460283
Abstract
40 patients with erosive rheumatoid arthritis (RA), 20 of whom were IgM-negative and 20 IgM-positive, were studied prospectively with regard to their association with HLA-B-CREGs (B5-, B8-, B12-, B16-, B27-CREG). We found a highly significant association of IgM-negative RA patients and B5-CREG-antigens (Chi2 = 28.6; p less than 0.001).
摘要
对40例糜烂性类风湿关节炎（RA）患者进行了前瞻性研究，以探讨其与HLA - B - CREGs（B5 -、B8 -、B12 -、B16 -、B27 - CREG）的关联，其中20例IgM阴性，20例IgM阳性。我们发现IgM阴性的RA患者与B5 - CREG抗原之间存在高度显著的关联（卡方检验= 28.6；p小于0.001）。
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