Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, Iowa.
J Occup Environ Hyg. 2021 Dec;18(12):579-589. doi: 10.1080/15459624.2021.1989443. Epub 2021 Nov 1.
The inhalable aerosol sampling criterion has been developed to characterize the efficiency of particles entering the nose and/or mouth. However, pesticides can exist in the air in both vapor and particulate phases, which complicates exposure assessments. The American Conference of Governmental Industrial Hygienists (ACGIH) has established an IFV (inhalable fraction and vapor) endnote for chemicals such as many pesticides that need to be evaluated for both their inhalable fraction and vapor concentrations to fully characterize worker exposures. The purpose of this study was to evaluate the particle-phase collection efficiency of a commonly-used pesticide sampler, the OSHA Versatile Sampler (OVS) as well as a recently developed sampler, the IFV Pro. The OVS was not designed as an inhalable aerosol sampler, whereas the IFV Pro contains a sampling head scaled to that of the Institute of Medicine (IOM) sampler, which is known to closely follow the inhalable sampling criterion. Laboratory experiments involving a vertical-flow, low-velocity scheme, and finely graded test dusts with known median aerodynamic diameter were used to determine sampler collection efficiencies. The collection efficiency of the OVS was evaluated as recommended by the manufacturer and after two modifications made to potentially improve its collection efficiency. The OVS was found to substantially under-sample relative to the inhalable criterion, and the two modifications did not provide substantial improvements to the original configuration. Conversely, the collection efficiency of the IFV Pro was found to compare closely to that of the IOM, although collecting 9% more mass. When applied side-by-side with the OVS sampler in a chamber into which ethylene glycol was sprayed as a proxy for a pesticide, the IFV Pro collected an average of 1.9-fold more mass than the OVS for the same flow rate and sample time.
可吸入气溶胶采样标准已被开发出来,用于描述进入鼻腔和/或口腔的颗粒的效率。然而,农药可以以蒸气和颗粒相两种形式存在于空气中,这使得暴露评估变得复杂。美国政府工业卫生学家会议(ACGIH)为许多需要同时评估其可吸入部分和蒸气浓度以充分描述工人暴露情况的化学物质建立了 IFV(可吸入部分和蒸气)的注释。本研究的目的是评估一种常用农药采样器(OSHA 多用采样器(OVS))和最近开发的采样器(IFV Pro)的颗粒相采集效率。OVS 不是专门设计为可吸入气溶胶采样器,而 IFV Pro 包含一个采样头,其尺寸与医学研究所(IOM)采样器相匹配,该采样器已知可紧密遵循可吸入采样标准。实验室实验涉及垂直流动、低风速方案以及具有已知中值空气动力学直径的精细分级测试粉尘,用于确定采样器的采集效率。按照制造商的建议评估了 OVS 的采集效率,并对其进行了两次修改,以提高其采集效率。结果发现,OVS 的采样量相对于可吸入标准明显不足,两次修改对原始配置并没有明显的改进。相比之下,IFV Pro 的采集效率与 IOM 非常接近,尽管它多收集了 9%的质量。当将 IFV Pro 与 OVS 采样器并排应用于一个室中,该室中喷入乙二醇作为农药的替代品时,IFV Pro 在相同的流速和采样时间下比 OVS 平均多收集了 1.9 倍的质量。