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高龄患者非体外循环冠状动脉旁路移植术的非体外循环第一策略的结果。

Results of off-pump coronary artery bypass grafting with off-pump first strategy in octogenarian.

机构信息

Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Aichi, Japan.

出版信息

J Card Surg. 2021 Dec;36(12):4611-4616. doi: 10.1111/jocs.16055. Epub 2021 Oct 6.

Abstract

BACKGROUND AND AIM

Ischemic heart disease is the leading cause of death around the world. Coronary artery bypass grafting offers efficient surgical revascularization for ischemic disease. Both on- or off-pump coronary artery bypass methods provide promising results to octogenarians, once complete vascularization is achieved. However, off-pump bypass requires a certain level of experience to achieve sufficient results. We have applied an off-pump coronary artery bypass-first strategy to all generations since 2008. This study investigated early and long-term results of surgical revascularization for octogenarians by a team with an off-pump-first strategy.

METHODS

All cases of isolated coronary artery bypass grafting performed since 2008 were identified and divided into a young group (age < 80 years) and an old group (age ≥ 80 years). Peri-operative results were investigated retrospectively in both groups and long-term results for the old group were assessed.

RESULTS

Among the 707 patients, 97% underwent off-pump bypass, and 94 cases were classified to the old group. Distal anastomoses and ventilator time were identical between groups (young vs. old: 3.3 vs. 3.2; 3.7 h vs. 3.7 h). In-hospital death rates were 0.5% and 0% in the young and old groups, respectively. With a mean follow-up of 1318 days, actual 1-, 3-, and 5-year survival rates for octogenarians were 92.1%, 81.2%, and 68.3%, respectively. Nearly half of the patients reached their nineties, which was close to the life expectancy of the national general octogenarian.

CONCLUSIONS

An experienced team with an off-pump-first strategy could provide valid therapeutic options for octogenarians.

摘要

背景与目的

缺血性心脏病是全球范围内主要的致死原因。冠状动脉旁路移植术为缺血性疾病提供了高效的手术血运重建。在实现完全血管化的前提下,无论是体外循环还是非体外循环的冠状动脉旁路方法都为 80 岁以上的患者提供了有前景的结果。然而,非体外循环旁路需要一定的经验水平才能获得足够的效果。自 2008 年以来,我们团队一直将非体外循环冠状动脉旁路优先策略应用于所有年龄段的患者。本研究调查了具有非体外循环优先策略的团队对 80 岁以上患者进行手术血运重建的早期和长期结果。

方法

回顾性调查了自 2008 年以来所有进行的单纯冠状动脉旁路移植术病例,并将其分为年轻组(年龄<80 岁)和老年组(年龄≥80 岁)。对两组患者的围手术期结果进行了回顾性研究,并对老年组的长期结果进行了评估。

结果

在 707 例患者中,97%的患者接受了非体外循环旁路,94 例患者被归入老年组。两组患者的远端吻合口和呼吸机使用时间相似(年轻组与老年组:3.3 比 3.2;3.7 小时比 3.7 小时)。院内死亡率分别为 0.5%和 0%,年轻组和老年组分别为 0.5%和 0%。平均随访 1318 天,80 岁以上患者的实际 1、3 和 5 年生存率分别为 92.1%、81.2%和 68.3%。近一半的患者达到了 90 多岁,接近全国 80 岁以上老年人的预期寿命。

结论

经验丰富的非体外循环优先策略团队可为 80 岁以上患者提供有效的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ce0/9291825/7e63323b7ef8/JOCS-36-4611-g001.jpg

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