Department of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Department of Neurology, University Medical Center Utrecht and de Hoogstraat Rehabilitation, Utrecht, The Netherlands.
Sci Rep. 2021 Oct 7;11(1):19985. doi: 10.1038/s41598-021-99484-6.
Traumatic brain injury (TBI) is a leading cause of death and disability. Epidemiology seems to be changing. TBIs are increasingly caused by falls amongst elderly, whilst we see less polytrauma due to road traffic accidents (RTA). Data on epidemiology is essential to target prevention strategies. A nationwide retrospective cohort study was conducted. The Dutch National Trauma Database was used to identify all patients over 17 years old who were admitted to a hospital with moderate and severe TBI (AIS ≥ 3) in the Netherlands from January 2015 until December 2017. Subgroup analyses were done for the elderly and polytrauma patients. 12,295 patients were included in this study. The incidence of moderate and severe TBI was 30/100.000 person-years, 13% of whom died. Median age was 65 years and falls were the most common trauma mechanism, followed by RTAs. Amongst elderly, RTAs consisted mostly of bicycle accidents. Mortality rates were higher for elderly (18%) and polytrauma patients (24%). In this national database more elderly patients who most often sustained the injury due to a fall or an RTA were seen. Bicycle accidents were very frequent, suggesting prevention could be an important aspect in order to decrease morbidity and mortality.
创伤性脑损伤（TBI）是导致死亡和残疾的主要原因。流行病学似乎正在发生变化。老年人因跌倒导致的 TBI 越来越多，而道路交通碰撞（RTA）导致的多发伤则越来越少。有关流行病学的数据对于确定预防策略至关重要。进行了一项全国性回顾性队列研究。荷兰国家创伤数据库用于识别 2015 年 1 月至 2017 年 12 月期间在荷兰因中度和重度 TBI（AIS ≥ 3）而住院的所有 17 岁以上的患者。对老年人和多发伤患者进行了亚组分析。本研究共纳入 12295 例患者。中度和重度 TBI 的发病率为 30/100000 人年，其中 13%的患者死亡。中位年龄为 65 岁，跌倒为最常见的创伤机制，其次是 RTA。在老年人中，RTA 主要由自行车事故引起。老年人（18%）和多发伤患者（24%）的死亡率更高。在这个国家数据库中，更多的老年人因跌倒或 RTA 受伤。自行车事故非常频繁，这表明预防可能是降低发病率和死亡率的一个重要方面。
