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小儿患者以偶然发现的肝脏肉芽肿为克罗恩病的首发表现

Incidental Hepatic Granulomata as the Initial Presentation of Crohn's Disease in a Pediatric Patient.

作者信息

Mostafavi Mojdeh, Sayej Wael, Hansen Blake, Cretara Anthony, Mueller James, Hirsch Barry

机构信息

Department of Internal Medicine and Pediatrics, University of Massachusetts Medical School-Baystate, Springfield, MA.

Department of Pediatric Gastroenterology & Nutrition, University of Massachusetts Medical School-Baystate, Springfield, MA.

出版信息

ACG Case Rep J. 2021 Oct 4;8(9):e00662. doi: 10.14309/crj.0000000000000662. eCollection 2021 Sep.

Abstract

We describe a 9-year-old girl who presented with abdominal pain, found incidentally to have multiple liver granulomata. Extensive autoimmune and infectious workup was negative. The patient had esophagogastroduodenoscopy and colonoscopy, confirming the diagnosis of Crohn's disease. Hepatic granulomata are a rare complication of Crohn's disease and are often secondary to pharmacotherapy or infection in immunosuppressed patients. This case, to our knowledge, is the first reported case of a pediatric patient diagnosed with Crohn's disease after initially presenting with hepatic granulomata as an extraintestinal manifestation of the disease.

摘要

我们描述了一名9岁女孩,她因腹痛就诊,偶然发现有多个肝脏肉芽肿。广泛的自身免疫和感染方面的检查结果均为阴性。该患者接受了食管胃十二指肠镜检查和结肠镜检查,确诊为克罗恩病。肝脏肉芽肿是克罗恩病的一种罕见并发症,在免疫抑制患者中常继发于药物治疗或感染。据我们所知,该病例是首例最初以肝脏肉芽肿作为该病肠外表现就诊后被诊断为克罗恩病的儿科患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa93/8492366/51dca51c9d29/ac9-8-e00662-g001.jpg

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