The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, China.
Center for Evidence Synthesis in Health, Brown University School of Public Health, Providence, RI, 02912, USA; Department of Social Medicine and Health Education, School of Public Health, Peking University, Peking, 100191, China.
Nutr Metab Cardiovasc Dis. 2021 Nov 29;31(12):3314-3321. doi: 10.1016/j.numecd.2021.08.033. Epub 2021 Aug 16.
High sodium intake is associated with a higher risk of a wide range of diseases. We aimed to estimate the pattern and trend of the global disease burden associated with high sodium intake from 1990 to 2019.
We obtained numbers and rates of death and disability-adjusted life year (DALY) attributable to high sodium intake by sex, socio-demographic index, and country from the Global Burden of Disease Study 2019. We calculated the estimated annual percentage change to evaluate the age-standardized rate (ASR) of the burden attributable to high sodium intake between 1990 and 2019. We further calculated the contribution of population growth, population aging, and age-specific rates of death and DALY to the net change in the total number of deaths and DALYs attributable to high sodium intake. From 1990 to 2019, global age-standardized rates of death and DALY attributable to high sodium intake substantially decreased for both sexes. However, there were significant increases in the total numbers of deaths and DALYs attributable to high sodium intake, which were driven by population growth and population aging. The attribution of population growth and population aging varied widely across countries, with a higher contribution of population growth in most developing countries and a higher contribution of population aging in countries with slow population growth.
Although the global burden attributable to high sodium intake in terms of age-standardized rate declined from 1990 to 2019, the absolute burden increased significantly, which was driven by population growth and population aging.
高钠摄入量与多种疾病的风险增加有关。我们旨在估计 1990 年至 2019 年期间与高钠摄入量相关的全球疾病负担模式和趋势。
我们从 2019 年全球疾病负担研究中获得了高钠摄入量导致的死亡人数和伤残调整生命年(DALY)的数量和比例,按性别、社会人口指数和国家进行了分类。我们计算了估计的年变化百分比,以评估 1990 年至 2019 年高钠摄入量负担的年龄标准化率(ASR)。我们进一步计算了人口增长、人口老龄化以及特定年龄死亡率和 DALY 对高钠摄入量所致总死亡人数和 DALY 净变化的贡献。1990 年至 2019 年期间,高钠摄入量导致的男女死亡率和 DALY 的年龄标准化率均大幅下降。然而,高钠摄入量所致死亡人数和 DALY 的总数显著增加,这主要是由人口增长和人口老龄化驱动的。人口增长和人口老龄化的归因在各国之间差异很大,在大多数发展中国家,人口增长的贡献较高,而在人口增长缓慢的国家,人口老龄化的贡献较高。
尽管 1990 年至 2019 年期间高钠摄入量的年龄标准化率全球负担有所下降,但绝对负担显著增加,这主要是由人口增长和人口老龄化驱动的。