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新旧人体测量指数与2型糖尿病及代谢并发症风险之间的关联:一项横断面分析研究。

Associations between new and old anthropometric indices with type 2 diabetes mellitus and risk of metabolic complications: a cross-sectional analytical study.

作者信息

Amiri Parichehr, Javid Ahmad Zare, Moradi Leila, Haghighat Neda, Moradi Rahim, Behbahani Hossein Bavi, Zarrin Milad, Bazyar Hadi

机构信息

Ahvaz Jundishapur University of Medical Sciences, Student Research Committee, Ahvaz, Iran.

Ahvaz Jundishapur University of Medical Sciences, School of Allied Medical Sciences, Department of Nutrition, Ahvaz, Iran.

出版信息

J Vasc Bras. 2021 Sep 20;20:e20200236. doi: 10.1590/1677-5449.200236. eCollection 2021.

Abstract

BACKGROUND

Obesity can increase the risk of diabetes mellitus and complications associated with it.

OBJECTIVES

The aim of this study was to estimate the associations between new and old anthropometric indices and the risk of type 2 diabetes mellitus (T2DM) and its metabolic complications.

METHODS

In this cross-sectional analytical study, 110 T2DM subjects and 110 healthy controls were selected by convenience sampling. Metabolic factors were evaluated including the atherogenic index of plasma (AIP), glycemic status, lipid profile, blood pressure, kidney indices, new anthropometric indices (abdominal volume index [AVI], body shape index [ABSI], lipid accumulation product [LAP], body adiposity index [BAI], and conicity index [CI]), and old anthropometric indices (weight, body mass index [BMI], and waist and hip circumference [WC and HC]).

RESULTS

Significant positive correlations were observed between AVI, LAP, and BAI and fasting blood glucose and HbA1c in the T2DM group (p < 0.001 for all associations). The odds ratio (OR) for T2DM elevated significantly with increasing BMI (OR: 1.30, 95% CI: 1.20-1.42), LAP (OR: 1.20, 95% CI: 1.13-1.27), and BAI (OR: 1.32, 95% CI: 1.21-1.43). The indices AVI (OR: 1.90, 95% CI: 1.57-2.29), LAP (OR: 1.19, 95% CI: 1.13-1.27), BAI (OR: 1.19, 95% CI: 1.12-1.26), WC (OR: 1.29, 95% CI: 1.18, 1.42), and HC (OR: 1.07, 95% CI: 1.01, 1.14) significantly increased the risk of metabolic syndrome (MetS).

CONCLUSIONS

Associations were identified between obesity indices and diabetes. These indices could be used in clinical practice for evaluation and control of T2DM.

摘要

背景

肥胖会增加糖尿病及其相关并发症的风险。

目的

本研究旨在评估新旧人体测量指标与2型糖尿病(T2DM)及其代谢并发症风险之间的关联。

方法

在这项横断面分析研究中,通过便利抽样选取了110名T2DM患者和110名健康对照者。评估了代谢因素,包括血浆致动脉粥样硬化指数(AIP)、血糖状态、血脂谱、血压、肾脏指标、新的人体测量指标(腹部容积指数[AVI]、体型指数[ABSI]、脂质蓄积产物[LAP]、体脂指数[BAI]和锥度指数[CI])以及旧的人体测量指标(体重、体重指数[BMI]、腰围和臀围[WC和HC])。

结果

在T2DM组中,观察到AVI、LAP和BAI与空腹血糖及糖化血红蛋白之间存在显著正相关(所有关联的p<0.001)。随着BMI(比值比[OR]:1.30,95%置信区间[CI]:1.20 - 1.42)、LAP(OR:1.20,95%CI:1.13 - 1.27)和BAI(OR:1.32,95%CI:1.21 - 1.43)升高,T2DM的OR显著升高。AVI(OR:1.90,95%CI:1.57 - 2.29)、LAP(OR:1.19,95%CI:1.13 - 1.27)、BAI(OR:1.19,95%CI:1.12 - 1.26)、WC(OR:1.29,95%CI:1.18,1.42)和HC(OR:1.07,95%CI:1.01,1.14)这些指标显著增加了代谢综合征(MetS)的风险。

结论

确定了肥胖指标与糖尿病之间的关联。这些指标可用于临床实践中评估和控制T2DM。

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