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佝偻病——并非仅是“英国病”。

Rickets--not only the "English disease".

作者信息

Belton N R

出版信息

Acta Paediatr Scand Suppl. 1986;323:68-75.

PMID:3463118
Abstract

Nutritional rickets in infancy and childhood due to vitamin D deficiency continues to be a world-wide problem. Its occurrence is probably higher in many tropical and sub-tropical countries, despite abundant sunlight than in many more northerly latitudes, where its incidence is mainly limited to children of Asian origin and those with dark skins. Social and cultural customs including the adherence to a special, often vegetarian diet, the avoidance of sunlight together with increasing urbanisation, extended breast feeding and severe malnutrition are recognisable factors in the pathogenesis of rickets. Recent research has suggested that the regulation of vitamin D metabolism may be different in black children compared with those who have a fair skin. Supplementation of mothers in pregnancy and of children in infancy with vitamin D together with health education to promote a diet containing foods rich in vitamin D can ameliorate this preventable disease.

摘要

婴儿期和儿童期因维生素D缺乏引起的营养性佝偻病仍是一个全球性问题。尽管阳光充足,但在许多热带和亚热带国家,其发病率可能高于许多高纬度地区,在这些高纬度地区,其发病率主要限于亚裔儿童和肤色较深的儿童。社会和文化习俗,包括坚持特殊的、通常是素食的饮食、避免阳光照射、城市化进程加快、延长母乳喂养以及严重营养不良,都是佝偻病发病机制中可识别的因素。最近的研究表明,与肤色浅的儿童相比,黑人儿童维生素D代谢的调节可能有所不同。孕期母亲和婴儿期儿童补充维生素D,同时进行健康教育以促进含有丰富维生素D食物的饮食,可以改善这种可预防的疾病。

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