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1975年以前非洲血清中不存在针对人类免疫缺陷病毒的抗体。

Absence of antibodies to the human immunodeficiency virus in sera from Africa prior to 1975.

作者信息

Levy J A, Pan L Z, Beth-Giraldo E, Kaminsky L S, Henle G, Henle W, Giraldo G

出版信息

Proc Natl Acad Sci U S A. 1986 Oct;83(20):7935-7. doi: 10.1073/pnas.83.20.7935.

Abstract

Three different assays for detection of antibodies to the human immunodeficiency virus (HIV) were conducted on 677 sera obtained from 1964 to 1975 from male and female children and adults in Uganda and other countries in Africa. Several sera were collected from individuals with Kaposi sarcoma. No evidence of antibodies to the virus was noted up to 1975. These results strongly suggest that the emergence of HIV in Africa occurred relatively recently. Further studies are required to determine the geographic origin of the acquired immunodeficiency syndrome virus.

摘要

对1964年至1975年间从乌干达和非洲其他国家的儿童及成人(包括男性和女性)身上采集的677份血清,进行了三种不同的检测人体免疫缺陷病毒(HIV)抗体的试验。从患有卡波西肉瘤的个体身上采集了几份血清。截至1975年,未发现该病毒抗体的迹象。这些结果有力地表明,HIV在非洲的出现相对较晚。需要进一步研究以确定获得性免疫缺陷综合征病毒的地理起源。

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