Patel Tulsi, Quow Krystina, Cardones Adela R
Duke University School of Medicine, Durham, NC 27710 USA.
Department of Dermatology, Duke University, Durham, NC 27710 USA.
Curr Dermatol Rep. 2021;10(4):232-242. doi: 10.1007/s13671-021-00334-5. Epub 2021 Oct 6.
There are various dermatologic emergencies stemming from bacterial, viral, and fungal etiologies that can present in the inpatient setting. This review summarizes the pathogenesis and diagnosis of infections with cutaneous involvement and highlights new therapies.
Clindamycin inhibits toxin formation and can be used as an adjunct therapy for the staphylococcal scalded syndrome. Isavuconazole therapy for mucormycosis infection is a less toxic alternative to amphotericin B.
Diagnosis of these infections is primarily guided by high clinical suspicion and early recognition can prevent dangerous sequelae. Treatment mainstays have been well-established, but there are adjunctive therapies that may potentially benefit the patient.
住院环境中可能出现多种由细菌、病毒和真菌病因引起的皮肤急症。本综述总结了伴有皮肤受累的感染的发病机制和诊断方法,并重点介绍了新的治疗方法。
克林霉素可抑制毒素形成,可作为葡萄球菌烫伤样皮肤综合征的辅助治疗药物。艾沙康唑治疗毛霉病感染是一种比两性霉素B毒性更低的替代疗法。
这些感染的诊断主要基于高度的临床怀疑,早期识别可预防危险的后遗症。治疗的主要方法已经确立,但一些辅助治疗可能对患者有益。