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住院皮肤科医生的感染性紧急情况管理

Management of Infectious Emergencies for the Inpatient Dermatologist.

作者信息

Patel Tulsi, Quow Krystina, Cardones Adela R

机构信息

Duke University School of Medicine, Durham, NC 27710 USA.

Department of Dermatology, Duke University, Durham, NC 27710 USA.

出版信息

Curr Dermatol Rep. 2021;10(4):232-242. doi: 10.1007/s13671-021-00334-5. Epub 2021 Oct 6.

DOI:10.1007/s13671-021-00334-5
PMID:34642610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8493951/
Abstract

PURPOSE OF REVIEW

There are various dermatologic emergencies stemming from bacterial, viral, and fungal etiologies that can present in the inpatient setting. This review summarizes the pathogenesis and diagnosis of infections with cutaneous involvement and highlights new therapies.

RECENT FINDINGS

Clindamycin inhibits toxin formation and can be used as an adjunct therapy for the staphylococcal scalded syndrome. Isavuconazole therapy for mucormycosis infection is a less toxic alternative to amphotericin B.

SUMMARY

Diagnosis of these infections is primarily guided by high clinical suspicion and early recognition can prevent dangerous sequelae. Treatment mainstays have been well-established, but there are adjunctive therapies that may potentially benefit the patient.

摘要

综述目的

住院环境中可能出现多种由细菌、病毒和真菌病因引起的皮肤急症。本综述总结了伴有皮肤受累的感染的发病机制和诊断方法，并重点介绍了新的治疗方法。

最新发现

克林霉素可抑制毒素形成，可作为葡萄球菌烫伤样皮肤综合征的辅助治疗药物。艾沙康唑治疗毛霉病感染是一种比两性霉素B毒性更低的替代疗法。

总结

这些感染的诊断主要基于高度的临床怀疑，早期识别可预防危险的后遗症。治疗的主要方法已经确立，但一些辅助治疗可能对患者有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/330d16ee1bdd/13671_2021_334_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/91cf56f40267/13671_2021_334_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/bbf48bbf9341/13671_2021_334_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/330d16ee1bdd/13671_2021_334_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/91cf56f40267/13671_2021_334_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/bbf48bbf9341/13671_2021_334_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b6/8493951/330d16ee1bdd/13671_2021_334_Fig3_HTML.jpg

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本文引用的文献

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Incidence of acute complications of herpes zoster among immunocompetent adults in England: a matched cohort study using routine health data.英格兰免疫功能正常成年人带状疱疹急性并发症的发病率：一项使用常规健康数据的匹配队列研究。
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