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收肌管阻滞联合 IPACK 阻滞用于全膝关节置换术后镇痛和功能恢复的前瞻性、双盲、随机对照研究。

Adductor Canal Block Combined With IPACK Block for Postoperative Analgesia and Function Recovery Following Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Study.

机构信息

Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

Department of Orthopedics, West China School of Nursing, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

出版信息

J Arthroplasty. 2022 Feb;37(2):259-266. doi: 10.1016/j.arth.2021.10.004. Epub 2021 Oct 13.

DOI:10.1016/j.arth.2021.10.004
PMID:34653576
Abstract

BACKGROUND

This study aimed to explore the analgesic effect among adductor canal block (ACB) combined with infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) block, ACB, and IPACK block following total knee arthroplasty (TKA).

METHODS

One hundred twenty patients were randomly allocated into 3 groups including group A (ACB + IPACK block), group B (ACB), and group C (IPACK block). The primary outcome was postoperative pain score. The secondary outcome was opioid consumption. Other outcomes included functional evaluation and postoperative complications.

RESULTS

Group A showed the lowest pain scores within 8 hours at rest and with knee maximum flexion (P < .001). From 12 to 24 hours, group C showed the highest pain scores, while no significant difference was found between group A and group B. No significant difference was found among the 3 groups 24 hours postoperatively. Group C showed the most opioid consumption within the first 24 hours and during the hospitalization, while no significant difference was found between group A and group B. No significant difference was found among the 3 groups including function evaluation and postoperative complications.

CONCLUSION

ACB + IPACK block can improve early analgesia when compared with ACB. However, the small statistical benefit to the addition of IPACK block to ACB may be unlikely to be clinically significant. Further studies may focus on patient selection and how to prolong the effect of IPACK block.

摘要

背景

本研究旨在探讨收肌管阻滞(ACB)联合膝关节后囊与腘窝之间浸润(IPACK)阻滞、ACB 和 IPACK 阻滞在全膝关节置换术后(TKA)的镇痛效果。

方法

将 120 名患者随机分为 3 组,包括 A 组(ACB+IPACK 阻滞)、B 组(ACB)和 C 组(IPACK 阻滞)。主要结局是术后疼痛评分。次要结局是阿片类药物的消耗量。其他结局包括功能评估和术后并发症。

结果

A 组在休息和膝关节最大屈曲时的 8 小时内疼痛评分最低(P<0.001)。从 12 小时到 24 小时,C 组疼痛评分最高,而 A 组和 B 组之间无显著差异。术后 24 小时 3 组之间无显著差异。C 组在 24 小时内和住院期间阿片类药物消耗量最高,而 A 组和 B 组之间无显著差异。3 组在功能评估和术后并发症方面无显著差异。

结论

与 ACB 相比,ACB+IPACK 阻滞可改善早期镇痛效果。然而,将 IPACK 阻滞添加到 ACB 中可能带来的小统计学益处不太可能具有临床意义。进一步的研究可能集中在患者选择和如何延长 IPACK 阻滞的效果上。

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