Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, s/n, 38206 San Cristóbal de La Laguna, España.
Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, s/n, 38206 San Cristóbal de La Laguna, España; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, s/n, 38206 San Cristóbal de La Laguna, España.
J Pharm Biomed Anal. 2022 Jan 5;207:114405. doi: 10.1016/j.jpba.2021.114405. Epub 2021 Oct 5.
The development of green sample preparation procedures is an extremely important research field in which more and more applications are constantly being proposed in different areas, including pharmaceutical analysis. This review article is aimed at providing a general overview of the development of miniaturized green analytical sample preparation procedures in the pharmaceutical analysis field, with special focus on the works published between January 2017 and July 2021. Particular attention has been paid to the application of environmentally friendly solvents and sorbents as well as nanomaterials or high extraction capacity sorbents in which the solvent volumes and reagents amounts are drastically reduced, with their subsequent advantages from the sustainability point of view.
绿色样品制备方法的发展是一个极其重要的研究领域，在不同领域（包括药物分析）中不断提出越来越多的应用。本文综述的目的是提供一个药物分析领域中微型化绿色分析样品制备方法发展的概述，特别关注 2017 年 1 月至 2021 年 7 月期间发表的工作。特别关注了环境友好型溶剂和吸附剂以及纳米材料或高萃取容量吸附剂的应用，其中大大减少了溶剂体积和试剂用量，并从可持续性的角度来看具有随后的优势。
