Filippou Olga, Bitas Dimitrios, Samanidou Victoria
Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 541 24 Greece.
Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 541 24 Greece.
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 1;1043:44-62. doi: 10.1016/j.jchromb.2016.08.040. Epub 2016 Aug 30.
Sample preparation is considered to be the most challenging step of the analytical procedure, since it has an effect on the whole analytical methodology, therefore it contributes significantly to the greenness or lack of it of the entire process. The elimination of the sample treatment steps, pursuing at the same time the reduction of the amount of the sample, strong reductions in consumption of hazardous reagents and energy also maximizing safety for operators and environment, the avoidance of the use of big amount of organic solvents, form the basis for greening sample preparation and analytical methods. In the last decade, the development and utilization of greener and sustainable microextraction techniques is an alternative to classical sample preparation procedures. In this review, the main green microextraction techniques (solid phase microextraction, stir bar sorptive extraction, hollow-fiber liquid phase microextraction, dispersive liquid - liquid microextraction, etc.) will be presented, with special attention to bioanalytical applications of these environment-friendly sample preparation techniques which comply with the green analytical chemistry principles.
样品制备被认为是分析过程中最具挑战性的步骤，因为它会对整个分析方法产生影响，因此对整个过程的绿色程度有着重大影响。消除样品处理步骤，同时减少样品量，大幅减少有害试剂和能源的消耗，并最大限度地提高操作人员和环境的安全性，避免使用大量有机溶剂，构成了绿色样品制备和分析方法的基础。在过去十年中，开发和利用更绿色、更可持续的微萃取技术是传统样品制备方法的一种替代方案。在这篇综述中，将介绍主要的绿色微萃取技术（固相微萃取、搅拌棒吸附萃取、中空纤维液相微萃取、分散液液微萃取等），特别关注这些符合绿色分析化学原则的环境友好型样品制备技术在生物分析中的应用。
