Oliver Marion John, Brereton Emily, Khan Muhib A, Davis Alan, Singer Justin
Department of Neurology, University of Toledo, Toledo, OH, United States.
College of Human Medicine, Michigan State University, East Lansing, MI, United States.
Front Neurol. 2021 Sep 29;12:677630. doi: 10.3389/fneur.2021.677630. eCollection 2021.
Our primary objective was to determine the successful rate of recanalization of M1 large vessel occlusion using either the Trevo 4 × 30 mm or 6 × 25 mm stent during mechanical thrombectomy. Our secondary objectives were to determine differences between the use of these two stent retrievers regarding first-pass effect, periprocedural complications, and mortality in the first 90 days. This is a retrospective cohort study. Data regarding the stent used, recanalization, number of passes, periprocedural complications, and mortality were determined our mechanical thrombectomy database along with chart review. When comparing Trevo 4 × 30 mm to 6 × 25 mm stent retrievers used in mechanical thrombectomy for middle cerebral artery large-vessel occlusion causing stroke, there is no statistically significant difference in successful recanalization rates, first-pass effect, perioperative complications, or mortality at 90 days. Studies like this will hopefully lead to further prospective, randomized controlled trials that will help show experts in the field an additional way to perform this procedure effectively and safely.
我们的主要目标是确定在机械取栓过程中使用Trevo 4×30 mm或6×25 mm支架对M1段大血管闭塞进行再通的成功率。我们的次要目标是确定这两种支架取栓器在首次通过效果、围手术期并发症以及90天内死亡率方面的差异。这是一项回顾性队列研究。通过我们的机械取栓数据库并结合病历审查,确定了有关所使用支架、再通情况、操作次数、围手术期并发症和死亡率的数据。在比较用于治疗因大脑中动脉大血管闭塞导致中风的机械取栓中的Trevo 4×30 mm和6×25 mm支架取栓器时,在成功再通率、首次通过效果、围手术期并发症或90天死亡率方面没有统计学上的显著差异。这样的研究有望促成进一步的前瞻性随机对照试验,这将有助于向该领域的专家展示另一种有效且安全地进行该手术的方法。