Wang Lin, Hsu Young, Sharma Neeraj
Nephrology, University of Southern California, Los Angeles, USA.
Internal Medicine, Keck School of Medicine, Los Angeles, USA.
Cureus. 2021 Sep 5;13(9):e17745. doi: 10.7759/cureus.17745. eCollection 2021 Sep.
Cytomegalovirus (CMV) infection is a common infectious complication after kidney transplantation. Indirect effects of CMV infection include an increased risk of secondary infections, increased risk of acute rejection, and chronic allograft dysfunction. However, it is not well known that CMV may also increase the risk of venous and arterial thrombosis. Here, we present a case of acute deep venous thromboembolism associated with acute CMV disease in a kidney transplant recipient. We also performed a literature review of cytomegalovirus-associated thrombosis in immunocompromised individuals.
巨细胞病毒(CMV)感染是肾移植后常见的感染性并发症。CMV感染的间接影响包括继发感染风险增加、急性排斥反应风险增加以及慢性移植肾失功。然而,CMV也可能增加静脉和动脉血栓形成的风险,这一点尚不为人熟知。在此,我们报告一例肾移植受者发生的与急性CMV疾病相关的急性深静脉血栓栓塞病例。我们还对免疫功能低下个体中与巨细胞病毒相关的血栓形成进行了文献综述。