College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Front Cell Infect Microbiol. 2021 Oct 1;11:751481. doi: 10.3389/fcimb.2021.751481. eCollection 2021.
As a common parasitic disease in animals, coccidiosis substantially affects the health of the host, even in the absence of clinical symptoms and intestinal tract colonization. Gut microbiota is an important part of organisms and is closely related to the parasite and host. Parasitic infections often have adverse effects on the host, and their pathogenic effects are related to the parasite species, parasitic site and host-parasite interactions. Coccidia-microbiota-host interactions represent a complex network in which changes in one link may affect the other two factors. Furthermore, coccidia-microbiota interactions are not well understood and require further research. Here, we discuss the mechanisms by which coccidia interact directly or indirectly with the gut microbiota and the effects on the host. Understanding the mechanisms underlying coccidia-microbiota-host interactions is important to identify new probiotic strategies for the prevention and control of coccidiosis.
作为一种常见的动物寄生虫病,球虫病严重影响宿主的健康,即使在没有临床症状和肠道定植的情况下也是如此。肠道微生物群是生物体的重要组成部分,与寄生虫和宿主密切相关。寄生虫感染通常对宿主有不良影响,其致病作用与寄生虫种类、寄生部位和宿主-寄生虫相互作用有关。球虫-微生物群-宿主相互作用代表了一个复杂的网络,其中一个环节的变化可能会影响其他两个因素。此外,球虫-微生物群相互作用还不太清楚,需要进一步研究。在这里,我们讨论了球虫直接或间接与肠道微生物群相互作用的机制以及对宿主的影响。了解球虫-微生物群-宿主相互作用的机制对于确定预防和控制球虫病的新益生菌策略非常重要。