Rao Sohail, Betancourt-Garcia Monica, Kare-Opaneye Yetunde O, Swierczewski Brett E, Bennett Jason W, Horne Bri'Anna, Fackler Joseph, Suazo Hernandez Lia Patricia, Brownstein Michael J
DHR Health Institute for Research & Development, Edinburg, Texas, USA.
College of Pharmacy, University of Houston, Houston, Texas, USA.
Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0082421. doi: 10.1128/AAC.00824-21. Epub 2021 Oct 18.
Hospitalized patients are at risk of developing serious multidrug resistant bacterial infections. This risk is heightened in patients who are on mechanical ventilation, are immunocompromised, and/or have chronic comorbidities. We report the case of a 52-year-old critically ill patient with a multidrug resistant Acinetobacter baumannii (MDR-A) respiratory infection who was successfully treated with antibiotics and intravenous and nebulized bacteriophage therapy.
住院患者有发生严重多重耐药细菌感染的风险。在接受机械通气、免疫功能低下和/或患有慢性合并症的患者中,这种风险会更高。我们报告了一例52岁的重症患者,该患者患有多重耐药鲍曼不动杆菌(MDR-A)呼吸道感染,通过抗生素以及静脉内和雾化噬菌体疗法成功治愈。