Lee Hyun Jung, Park Joon Young, Kim So Young, Hwang Chung Su, Lee Jung Hee, Shin Dong Hoon, Kim Jee Yeon
Department of Pathology, School of Medicine, Pusan National University, Yangsan, Korea.
The Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.
J Pathol Transl Med. 2021 Nov;55(6):410-414. doi: 10.4132/jptm.2021.09.11. Epub 2021 Oct 20.
Testicular carcinoid tumors are very rare, accounting for less than 1% of all testicular tumors. We report a rare case of a testicular carcinoid tumor with extensive lymphatic invasion. A 42-year-old man presented with a painless, enlarged right testicular mass. There was no history of injury or discomfort in this region. Right radical orchiectomy was performed, which showed a well-defined, non-encapsulated solid white mass with calcification (7.0 × 4.5 × 3.5 cm) and absence of cystic components. Microscopic examination using hematoxylin and eosin staining of the tumor sections identified organoid, trabecular, and solid patterns with rosette formation. Extensive multifocal lymphatic invasion was observed. Immunohistochemistry was positive for synaptophysin, chromogranin, and CD56. Testicular carcinoid tumors usually show good prognoses; however, there was extensive lymphovascular invasion in this case. Thus, in the case of unusual presentation of the disease, close follow-up is necessary.
睾丸类癌肿瘤非常罕见，占所有睾丸肿瘤的比例不到1%。我们报告一例罕见的伴有广泛淋巴浸润的睾丸类癌肿瘤病例。一名42岁男性因右侧睾丸无痛性肿大肿块就诊。该区域无损伤或不适病史。实施了右侧根治性睾丸切除术，术中见一界限清楚、无包膜的实性白色肿块，伴有钙化（7.0×4.5×3.5 cm），无囊性成分。对肿瘤切片进行苏木精-伊红染色的显微镜检查发现有器官样、小梁状和实性结构，并伴有菊形团形成。观察到广泛的多灶性淋巴浸润。免疫组化显示突触素、嗜铬粒蛋白和CD56呈阳性。睾丸类癌肿瘤通常预后良好；然而，该病例存在广泛的淋巴管浸润。因此，对于该病的不寻常表现，密切随访是必要的。
