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J Indian Soc Periodontol. 2021 Sep-Oct;25(5):418-421. doi: 10.4103/jisp.jisp_509_20. Epub 2021 Aug 30.
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本文引用的文献

1
Antioxidant and antimicrobial potential of selected varieties of Piper betle L. (Betel leaf).蒌叶(Piper betle L.)选定品种的抗氧化和抗菌潜力。
An Acad Bras Cienc. 2018 Oct-Dec;90(4):3871-3878. doi: 10.1590/0001-3765201820180285. Epub 2018 Oct 18.
2
Chlorhexidine mouthwash as an adjunct to mechanical therapy in chronic periodontitis: A meta-analysis.洗必泰含漱液辅助机械疗法治疗慢性牙周炎的疗效:一项荟萃分析。
J Am Dent Assoc. 2017 May;148(5):308-318. doi: 10.1016/j.adaj.2017.01.021. Epub 2017 Mar 9.
3
Efficacy of chlorhexidine and green tea mouthwashes in the management of dental plaque-induced gingivitis: A comparative clinical study.洗必泰和绿茶漱口水在治疗牙菌斑性牙龈炎中的疗效:一项对比临床研究。
Contemp Clin Dent. 2015 Oct-Dec;6(4):505-9. doi: 10.4103/0976-237X.169845.
4
Are herbal mouthwash efficacious over chlorhexidine on the dental plaque?草药漱口水在减少牙菌斑方面比氯己定更有效吗?
Pharmacognosy Res. 2015 Jul-Sep;7(3):277-81. doi: 10.4103/0974-8490.155874.
5
Comparison of the effectiveness of a commercially available herbal mouthrinse with chlorhexidine gluconate at the clinical and patient level.在临床和患者层面比较一种市售草本漱口水与葡萄糖酸洗必泰的有效性。
J Indian Soc Periodontol. 2011 Oct;15(4):349-52. doi: 10.4103/0972-124X.92567.
6
Periodontitis: a polymicrobial disruption of host homeostasis.牙周炎:一种宿主内稳态的微生物多样性破坏。
Nat Rev Microbiol. 2010 Jul;8(7):481-90. doi: 10.1038/nrmicro2337.
7
Evaluation of the antimicrobial, antioxidant, and anti-inflammatory activities of hydroxychavicol for its potential use as an oral care agent.对羟基查耳酮作为口腔护理剂的潜在用途进行抗菌、抗氧化和抗炎活性评估。
Antimicrob Agents Chemother. 2009 Jan;53(1):216-22. doi: 10.1128/AAC.00045-08. Epub 2008 Jun 23.
8
Use of phytotherapy in dentistry.植物疗法在牙科中的应用。
Phytother Res. 2008 Aug;22(8):993-8. doi: 10.1002/ptr.2471.
9
Reevaluation of initial therapy: when is the appropriate time?初始治疗的重新评估:何时为合适时机?
J Periodontol. 2006 Sep;77(9):1598-601. doi: 10.1902/jop.2006.050358.
10
Effect of chlorhexidine on the adherence properties of Porphyromonas gingivalis.洗必泰对牙龈卟啉单胞菌黏附特性的影响。
J Clin Periodontol. 1996 Feb;23(2):140-2. doi: 10.1111/j.1600-051x.1996.tb00547.x.

胡椒提取物漱口水作为牙周炎患者术后冲洗液对[相关物质]水平的影响。(原文中“levels of ”部分缺失具体内容)

Effect of piper extract mouthwash as postprocedural rinse on levels of in periodontitis patients.

作者信息

Sundaram Gopalakrishnan, Theagarajan Ramakrishnan, Murthy Gomathi Dhakshina, Kanimozhi Gopalakrishnan

机构信息

Department of Periodontics, Thai Moogambigai Dental College and Hospital Chennai, Tamil Nadu, India.

Department of Periodontics, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India.

出版信息

J Indian Soc Periodontol. 2021 Sep-Oct;25(5):418-421. doi: 10.4103/jisp.jisp_509_20. Epub 2021 Aug 30.

DOI:10.4103/jisp.jisp_509_20
PMID:34667385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8452170/
Abstract

BACKGROUND

Dental biofilm plays a crucial role in periodontal disease development. Mouth rinse is used to enhance oral hygiene after scaling and root planning (SRP). The aim of the study was to evaluate the clinical and microbiological effectiveness of a piper extract mouthwash against Chlorhexidine (CHX) in periodontitis patients.

MATERIALS AND METHODS

Sixty patients with Stage II periodontitis participated in this study and were randomly divided into two groups (Group I - Stage II Grade A periodontitis patients were provided with prepared piper extract mouthwash and Group II - Stage II Grade A periodontitis patients were provided with 0.2% CHX). Plaque index, gingival index, sulcus bleeding index, probing pocket depth, and clinical attachment level were recorded at baseline and 30 days after SRP. Subgingival plaque samples were taken for microbial examination (colony-forming unit), quantification of using the real-time polymerase chain reaction at baseline, and 30 days after SRP.

RESULTS

Intragroup comparison for the clinical parameters showed statistically significant reduction in both the groups ( < 0.0001). Intergroup comparison for clinical parameters, there was no statistical significance seen after 30 days. Intragroup comparison for microbial analysis showed significant reduction in both the groups after 30 days ( < 0.0001). On intergroup comparison for microbial analysis, both the groups showed reduction after 30 days without significance.

CONCLUSION

Piper extract mouthwash (Group I) showed similar antimicrobial activity against when compared to 0.2% CHX mouthwash (Group II) that could be used as a substitute to CHX.

摘要

背景

牙菌斑在牙周疾病发展中起关键作用。漱口水用于在龈下刮治和根面平整(SRP)后增强口腔卫生。本研究的目的是评估胡椒提取物漱口水对牙周炎患者中氯己定(CHX)的临床和微生物学有效性。

材料与方法

60例II期牙周炎患者参与本研究,并随机分为两组(I组 - II期A级牙周炎患者使用制备好的胡椒提取物漱口水,II组 - II期A级牙周炎患者使用0.2% CHX)。在基线和SRP后30天记录菌斑指数、牙龈指数、龈沟出血指数、探诊袋深度和临床附着水平。采集龈下菌斑样本进行微生物检查(菌落形成单位),在基线和SRP后30天使用实时聚合酶链反应进行定量。

结果

两组临床参数的组内比较均显示有统计学意义的降低(<0.0001)。临床参数的组间比较在30天后未见统计学意义。微生物分析的组内比较显示两组在30天后均有显著降低(<0.0001)。微生物分析的组间比较显示两组在30天后均有降低但无显著性。

结论

与0.2% CHX漱口水(II组)相比,胡椒提取物漱口水(I组)对[具体微生物]显示出相似的抗菌活性,可作为CHX的替代品。