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Diastolic Blood Pressure and the J-Curve-Causal Effect or Confounding?

作者信息

Hartsell Sydney E, Beddhu Srinivasan

机构信息

Division of Nephrology and Hypertension, Department of Medicine, University of Utah School of Medicine, Salt Lake City.

出版信息

JAMA Netw Open. 2021 Oct 1;4(10):e2130031. doi: 10.1001/jamanetworkopen.2021.30031.

DOI:10.1001/jamanetworkopen.2021.30031
PMID:34668952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8967343/
Abstract
摘要

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Association Between Baseline Diastolic Blood Pressure and the Efficacy of Intensive vs Standard Blood Pressure-Lowering Therapy.基础舒张压与强化降压治疗与标准降压治疗疗效的关系。
JAMA Netw Open. 2021 Oct 1;4(10):e2128980. doi: 10.1001/jamanetworkopen.2021.28980.
2
The Influence of Baseline Diastolic Blood Pressure on the Effects of Intensive Blood Pressure Lowering on Cardiovascular Outcomes and All-Cause Mortality in Type 2 Diabetes.基础舒张压对强化降压对 2 型糖尿病心血管结局和全因死亡率影响的影响。
Diabetes Care. 2020 Aug;43(8):1878-1884. doi: 10.2337/dc19-2047. Epub 2020 May 4.
3
Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT.强化收缩压降压治疗对标准血糖控制的 2 型糖尿病患者及无糖尿病患者心血管事件和死亡率的影响：来自 ACCORD BP 和 SPRINT 的结果再分析。
J Am Heart Assoc. 2018 Sep 18;7(18):e009326. doi: 10.1161/JAHA.118.009326.
4
Influence of Baseline Diastolic Blood Pressure on Effects of Intensive Compared With Standard Blood Pressure Control.基础舒张压对强化与标准血压控制效果影响的研究。
Circulation. 2018 Jan 9;137(2):134-143. doi: 10.1161/CIRCULATIONAHA.117.030848. Epub 2017 Oct 11.
5
J Curve in Patients Randomly Assigned to Different Systolic Blood Pressure Targets: An Experimental Approach to an Observational Paradigm.随机分配至不同收缩压目标的患者中的 J 型曲线：观察性范例的实验方法。
Circulation. 2017 Dec 5;136(23):2220-2229. doi: 10.1161/CIRCULATIONAHA.117.030342. Epub 2017 Sep 22.
6
A Randomized Trial of Intensive versus Standard Blood-Pressure Control.强化与标准血压控制的随机试验
N Engl J Med. 2015 Nov 26;373(22):2103-16. doi: 10.1056/NEJMoa1511939. Epub 2015 Nov 9.
7
The myocardial oxygen supply:demand index revisited.心肌氧供与需求指数再探讨。
J Am Heart Assoc. 2014 Jan 21;3(1):e000285. doi: 10.1161/JAHA.113.000285.
8
Effects of intensive blood-pressure control in type 2 diabetes mellitus.强化血压控制对 2 型糖尿病的影响。
N Engl J Med. 2010 Apr 29;362(17):1575-85. doi: 10.1056/NEJMoa1001286. Epub 2010 Mar 14.
9
Effects of intensive glucose lowering in type 2 diabetes.强化降糖对2型糖尿病的影响。
N Engl J Med. 2008 Jun 12;358(24):2545-59. doi: 10.1056/NEJMoa0802743. Epub 2008 Jun 6.
10
Benefits and potential harm of lowering high blood pressure.降低高血压的益处与潜在危害。
Lancet. 1987 Mar 14;1(8533):581-4. doi: 10.1016/s0140-6736(87)90231-5.