Yuan Yongping, Zhao Jiajia, He Nv
Oral Teaching and Research Office, Ningbo Colloge of Health Sciences, Ningbo, Zhejiang 315100, China.
Department of Dental, Zhuji People's Hospital, Zhuji, Zhejiang 311800, China.
Evid Based Complement Alternat Med. 2021 Oct 12;2021:1743677. doi: 10.1155/2021/1743677. eCollection 2021.
To investigate the curative effect of guided tissue regeneration (GTR) combined with bone grafting and improve the aesthetic appearance of patients' gingiva.
A total of 86 patients with periodontal intraosseous defects were selected from February 2019 to February 2021. All the patients were divided into a control group and an observation group according to the random number table, with 43 patients in each group. Bone grafting was performed in the control group, while GTR was additionally used in the observation group on the basis of the control group. The surgical data and follow-up data were collected and organized. The alveolar bone mineral density, the change in the height of the bone defect, plaque index (PLI), sulcus hemorrhage index (SBI), PD, gingival recession (GR), clinical attachment loss (CAL), and other relevant data of the two groups in 6 months before and after surgery were compared. Six months after surgery, the cosmetic morphology of the patient's gums in the soft tissues around her teeth was evaluated.
Six months after surgery, the alveolar bone density of patients in two groups increased compared with that before surgery, and the height of the bone defect decreased compared with that before surgery. The alveolar bone density of the observation group was higher than that of the control group, and the height of the bone defect was lower than that of the control group ( < 0.05). Six months after surgery, the PLI, SBI, PD, and CAL of patients in both groups were lower than those before surgery, while the GR was higher than that before surgery. PD and CAL values in the observation group were lower than those in the control group, and GR was higher than that in the control group ( < 0.05). Six months after surgery, there was no significant difference in PLI and SBI scores between the two groups ( < 0.05). Six months after surgery, the gingival cosmetic scores of the two groups of patients were higher than those before surgery. The observation group was higher than the control group ( < 0.05).
GTR combined with bone grafting has a good effect in the repair of periodontal intraosseous defects and can effectively promote the reconstruction and recovery of periodontal intraosseous defects in patients. At the same time, it can significantly improve the aesthetic appearance of patients' gums, with good clinical application value.
探讨引导组织再生术（GTR）联合骨移植的疗效，并改善患者牙龈的美观度。
选取2019年2月至2021年2月期间86例牙周骨内缺损患者。根据随机数字表将所有患者分为对照组和观察组，每组43例。对照组进行骨移植，观察组在对照组基础上额外使用GTR。收集并整理手术数据和随访数据。比较两组患者手术前后6个月的牙槽骨密度、骨缺损高度变化、菌斑指数（PLI）、龈沟出血指数（SBI）、牙周袋深度（PD）、牙龈退缩（GR）、临床附着丧失（CAL）等相关数据。术后6个月，评估患者牙齿周围软组织中牙龈的美容形态。
术后6个月，两组患者的牙槽骨密度均较术前增加，骨缺损高度较术前降低。观察组的牙槽骨密度高于对照组，骨缺损高度低于对照组（P<0.05）。术后6个月，两组患者的PLI、SBI、PD和CAL均低于术前，而GR高于术前。观察组的PD和CAL值低于对照组，GR高于对照组（P<0.05）。术后6个月，两组间PLI和SBI评分差异无统计学意义（P>0.05）。术后6个月，两组患者的牙龈美容评分均高于术前。观察组高于对照组（P<0.05）。
GTR联合骨移植在牙周骨内缺损修复中效果良好，能有效促进患者牙周骨内缺损的重建与恢复。同时，可显著改善患者牙龈的美观度，具有良好的临床应用价值。
