School of Materials Science & Engineering, Nanyang Technological University, Singapore, 639798, Singapore.
School of Mechanical Engineering & Key Laboratory of Materials Design and Preparation Technology of Hunan Province, Xiangtan University, Xiangtan, 411105, China.
Microb Biotechnol. 2022 Feb;15(2):548-560. doi: 10.1111/1751-7915.13891. Epub 2021 Oct 22.
The recent COVID-19 virus has led to a rising interest in antimicrobial and antiviral coatings for frequently touched surfaces in public and healthcare settings. Such coatings may have the ability to kill a variety of microorganisms and bio-structures and reduce the risk of virus transmission. This paper proposes an extremely rapid method to introduce rare-earth doping nano-ZnO in polyamines for the preparation of the anti-microbial polyurea coatings. The nano-ZnO is prepared by wet chemical method, and the RE-doped nano-ZnO was obtained by mixing nano ZnO and RE-dopants with an appropriate amount of nitric acid. This rapidly fabricated polyurea coating can effectively reduce bacteria from enriching on the surface. Comparing with pure nano-ZnO group, all the polyurea coatings with four different rare-earth elements (La, Ce, Pr and Gd) doped nano-ZnO. The La-doped nano-ZnO formula group indicates the highest bactericidal rate over 85% to Escherichia coli (E. coli) and Pseudomonas aeruginosa (Pseudomonas). Followed by Ce/ZnO, the bactericidal rate may still remain as high as 83% at room temperature after 25-min UV-exposure. It is believed that the RE-doping process may greatly improve the photocatalytic response to UV light as well as environmental temperature due to its thermal catalytic enhancement. Through the surface characterizations and bioassays, the coatings have a durably high bactericidal rate even after repeated usage. As polyurea coating itself has high mechanical strength and adhesive force with most substrate materials without peel-off found, this rapid preparation method will also provide good prospects in practical applications.
最近的 COVID-19 病毒引起了人们对公共和医疗环境中频繁接触表面的抗菌和抗病毒涂层的兴趣。这种涂层可能具有杀死多种微生物和生物结构的能力，并降低病毒传播的风险。本文提出了一种极快的方法，即将稀土掺杂纳米 ZnO 引入聚胺中，用于制备抗菌聚脲涂层。纳米 ZnO 通过湿化学方法制备，通过将纳米 ZnO 和 RE 掺杂剂与适量的硝酸混合，得到 RE 掺杂纳米 ZnO。这种快速制备的聚脲涂层可以有效地减少细菌在表面的富集。与纯纳米 ZnO 组相比，所有含有四种不同稀土元素（La、Ce、Pr 和 Gd）掺杂纳米 ZnO 的聚脲涂层。La 掺杂纳米 ZnO 配方组对大肠杆菌（E. coli）和铜绿假单胞菌（Pseudomonas）的杀菌率超过 85%。其次是 Ce/ZnO，在 25 分钟的紫外线照射后，室温下的杀菌率仍可能高达 83%。据信，由于其热催化增强，RE 掺杂过程可能会大大提高对紫外线和环境温度的光催化响应。通过表面特性和生物测定，即使经过多次使用，涂层仍具有持久的高杀菌率。由于聚脲涂层本身具有很高的机械强度和与大多数基底材料的附着力，没有发现剥落现象，这种快速制备方法在实际应用中也将有很好的前景。
