School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200003, China.
Shanghai Skin Disease Hospital, Shanghai 200040, China.
Int J Environ Res Public Health. 2021 Oct 19;18(20):10980. doi: 10.3390/ijerph182010980.
Ensuring adherence guarantees the efficacy of pre-exposure prophylaxis (PrEP).
We conducted a cross-sectional study among 816 sexually transmitted infection (STI) patients in Shanghai. The questionnaire included self-reported demographic characteristics, self-administered items on adherence to free oral PrEP, and PrEP uptake behavior measurement. We conducted item analysis, reliability analysis, validity analysis and receiver operating characteristic (ROC) curve analysis.
Not all items were considered acceptable in the item analysis. The questionnaire had a McDonald's ω coefficient of 0.847. The scale-level content validity index (CVI) was 0.938 and the item-level CVI of each item ranged from 0.750 to 1. In exploratory factor analysis, we introduced a four-factor model accounting for 79.838% of the aggregate variance, which was validated in confirmatory factor analysis. Adding PrEP adherence questionnaire scores contributed to prediction of PrEP uptake behavior ( < 0.001) in regression analysis. The maximum area under the ROC curve was 0.778 (95% IC: 0.739-0.817).
The PrEP adherence questionnaire presented psychometric validation among STI patients.
确保依从性可保证暴露前预防（PrEP）的疗效。
我们在上海的 816 名性传播感染（STI）患者中进行了一项横断面研究。问卷包括自我报告的人口统计学特征、自我管理的免费口服 PrEP 依从性项目以及 PrEP 摄取行为测量。我们进行了项目分析、信度分析、效度分析和受试者工作特征（ROC）曲线分析。
并非所有项目在项目分析中都被认为是可接受的。问卷的 McDonald's ω系数为 0.847。量表水平的内容效度指数（CVI）为 0.938，每个项目的项目水平 CVI 范围为 0.750 至 1。在探索性因子分析中，我们引入了一个可解释总方差 79.838%的四因素模型，该模型在验证性因子分析中得到了验证。在回归分析中，增加 PrEP 依从性问卷评分有助于预测 PrEP 摄取行为（<0.001）。ROC 曲线下的最大面积为 0.778（95%CI：0.739-0.817）。
PrEP 依从性问卷在 STI 患者中具有心理测量学验证。
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