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用于暴露前预防(PrEP)的适应性依从性自我效能量表的心理测量评估及预测效度

Psychometric Evaluation and Predictive Validity of an Adapted Adherence Self-Efficacy Scale for PrEP.

作者信息

Golub Sarit A, Starbuck Lila, Fikslin Rachel, Gamarel Kristi E

机构信息

Department of Psychology, Hunter College of the City University of New York, 695 Park Avenue, New York, NY, 10065, USA.

Basic and Applied Social Psychology PhD Program, Department of Psychology, Graduate Center of the City University of New York, New York, NY, USA.

出版信息

AIDS Behav. 2023 Jan;27(1):218-230. doi: 10.1007/s10461-022-03758-7. Epub 2022 Jul 9.

DOI:10.1007/s10461-022-03758-7
PMID:35809144
Abstract

Adherence to and sustainment of HIV pre-exposure prophylaxis (PrEP) are critical to its effectiveness. Adherence self-efficacy, i.e., confidence in one's ability to adhere to a particular medication, is a key psychological determinant of health behavior that strongly predicts HIV treatment adherence but has been understudied in PrEP research. This paper describes the psychometric evaluation and validation of the PrEP Adherence Self-Efficacy Scale (PrEP-ASES), adapted from the previously validated HIV Treatment Adherence Self-Efficacy Scale (HIV-ASES). Data are drawn from two studies conducted at a community health center, one focused on gay and bisexual cisgender men and the other on transgender women. Factor analyses support a one-factor score (eigenvalue = 6.78) that explained 75.3% of the variance, with good test-retest reliability (rs > 0.40). In both studies, higher PrEP-ASES scores were associated with PrEP uptake, adherence, and sustainment. Findings support the utility of the PrEP-ASES in research and suggest the importance of addressing self-efficacy in PrEP programs and services.

摘要

坚持和持续使用艾滋病毒暴露前预防药物(PrEP)对其有效性至关重要。坚持自我效能感,即对自己坚持服用特定药物能力的信心,是健康行为的关键心理决定因素,它能有力地预测艾滋病毒治疗的依从性,但在PrEP研究中尚未得到充分研究。本文描述了从先前验证的艾滋病毒治疗依从性自我效能量表(HIV-ASES)改编而来的PrEP依从性自我效能量表(PrEP-ASES)的心理测量评估和验证。数据来自在一个社区卫生中心进行的两项研究,一项针对男同性恋和双性恋顺性别男性,另一项针对跨性别女性。因子分析支持一个单因子得分(特征值 = 6.78),该得分解释了75.3%的方差,具有良好的重测信度(rs > 0.40)。在两项研究中,较高的PrEP-ASES得分都与PrEP的采用、依从性和持续性相关。研究结果支持PrEP-ASES在研究中的实用性,并表明在PrEP项目和服务中解决自我效能感问题的重要性。

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