McLaughlin J K, Malker H S, Blot W J, Malker B K, Stone B J, Weiner J A, Ericsson J L, Fraumeni J F
J Natl Cancer Inst. 1987 Feb;78(2):253-7.
With the use of the Cancer-Environment Registry, which links cancer incidence for the years 1961-79 with 1960 census information on occupation for all employed individuals in Sweden, a systematic population-based assessment according to employment classifications was made of the occurrence of intracranial gliomas. Statistically significant (P less than .05) increases in the incidence of intracranial gliomas were observed among several professional and white-collar occupations, possibly due in part to higher levels of diagnosis and reporting of this particular neoplasm. Significantly elevated rates were noted among male dentists, agricultural research workers, and public prosecutors and among female physicians and employees in the health care industry. For blue-collar workers, significant excesses were found among welders and metal cutters; glass, porcelain, or ceramic workers; cellulose plant employees; brick and tile workers; and women employed in the wool industry. Several findings of this survey may represent new clues to the etiology of intracranial gliomas, while other findings support observations reported in previous studies.
利用癌症-环境登记处（该登记处将1961年至1979年的癌症发病率与瑞典所有就业人员1960年的职业普查信息相联系），根据就业分类对颅内胶质瘤的发病情况进行了基于人群的系统评估。在几个专业和白领职业中观察到颅内胶质瘤发病率有统计学显著升高（P小于0.05），这可能部分归因于对这种特定肿瘤的诊断和报告水平较高。在男性牙医、农业研究人员和检察官以及女性医生和医疗行业雇员中，发病率显著升高。对于蓝领工人，在焊工和金属切割工、玻璃、瓷器或陶瓷工人、纤维素工厂雇员、砖瓦工以及羊毛行业就业的女性中发现发病率显著过高。本次调查的一些发现可能代表了颅内胶质瘤病因学的新线索，而其他发现则支持了先前研究报告的观察结果。
