• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

利妥昔单抗治疗皮肤型系统性红斑狼疮伴发的水疱大疱性疾病：一例报告

Vesiculobullous disease with Cutaneous Systemic Lupus Erythematosus Treated by Rituximab: A case report.

作者信息

Mohammed Niamat Alla Wigdan, Mohamed Ali Ahmed Burhan, Adam Essa Mohammed Elmujtba, Abdalla Babker Atif Elhadi, Mohammed Elagib Elnour

机构信息

Department of Rheumatology Sudan Medical Specialization Board Khartoum Sudan.

Department of Clinical Medicine Medical and Cancer Research Institute Khartoum Sudan.

出版信息

Clin Case Rep. 2021 Oct 15;9(10):e04967. doi: 10.1002/ccr3.4967. eCollection 2021 Oct.

DOI:10.1002/ccr3.4967
PMID:34691464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8517575/
Abstract

Vesiculobullous lesions in systemic lupus erythematosus (SLE) are a rare cutaneous manifestation of cutaneous and/or systemic LE with variable presentation. The diagnosis of SLE-associated vesiculobullous diseases remains challenging, due to the poorly defined similarities and nosology in immunohistopathological and clinical and features.

摘要

系统性红斑狼疮（SLE）中的水疱大疱性皮损是皮肤型和/或系统性红斑狼疮罕见的皮肤表现，其表现多样。由于免疫组织病理学、临床及特征方面的相似性和疾病分类定义不明确，SLE相关水疱大疱性疾病的诊断仍然具有挑战性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/a76ef2fd8456/CCR3-9-e04967-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/6a457616dc74/CCR3-9-e04967-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/9501822d09ce/CCR3-9-e04967-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/a76ef2fd8456/CCR3-9-e04967-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/6a457616dc74/CCR3-9-e04967-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/9501822d09ce/CCR3-9-e04967-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae34/8517575/a76ef2fd8456/CCR3-9-e04967-g004.jpg

相似文献

1
Vesiculobullous disease with Cutaneous Systemic Lupus Erythematosus Treated by Rituximab: A case report.利妥昔单抗治疗皮肤型系统性红斑狼疮伴发的水疱大疱性疾病：一例报告
Clin Case Rep. 2021 Oct 15;9(10):e04967. doi: 10.1002/ccr3.4967. eCollection 2021 Oct.
2
Vesiculobullous diseases in relation to lupus erythematosus.与红斑狼疮相关的水疱大疱性疾病
Clin Cosmet Investig Dermatol. 2019 Sep 4;12:653-667. doi: 10.2147/CCID.S220906. eCollection 2019.
3
Bullous systemic lupus erythematosus successfully treated with rituximab.利妥昔单抗成功治疗大疱性系统性红斑狼疮。
Cutis. 2019 Jun;103(6):E5-E7.
4
The differential panorama of clinical features of lupus erythematosus patients with different onset ages: a cross-sectional multicenter study from China.不同发病年龄红斑狼疮患者的临床特征差异全景：来自中国的一项横断面多中心研究。
Clin Rheumatol. 2023 Sep;42(9):2353-2367. doi: 10.1007/s10067-023-06661-1. Epub 2023 Jun 13.
5
Brief report: responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus.简要报告：利妥昔单抗治疗反应提示皮肤型系统性红斑狼疮中存在 B 细胞非依赖性炎症。
Arthritis Rheumatol. 2015 Jun;67(6):1586-91. doi: 10.1002/art.39085.
6
Clusters of clinical and immunologic features in patients with bullous systemic lupus erythematosus: experience from a single-center cohort study in China.大疱性系统性红斑狼疮患者的临床和免疫学特征簇：来自中国单中心队列研究的经验。
Orphanet J Rare Dis. 2022 Jul 23;17(1):290. doi: 10.1186/s13023-022-02445-z.
7
Atypical and Rare Forms of Cutaneous Lupus Erythematosus: The Importance of the Diagnosis for the Best Management of Patients.非典型和罕见形式的皮肤红斑狼疮：诊断对于患者最佳管理的重要性。
Dermatology. 2022;238(2):195-204. doi: 10.1159/000515766. Epub 2021 Jun 3.
8
Cutaneous lupus erythematosus: issues in diagnosis and treatment.皮肤红斑狼疮：诊断与治疗中的问题
Am J Clin Dermatol. 2009;10(6):365-81. doi: 10.2165/11310780-000000000-00000.
9
Bullous Systemic Lupus Erythematosus Successfully Treated With Intravenous Immunoglobulin and Mycophenolate Mofetil.静脉注射免疫球蛋白和霉酚酸酯成功治疗大疱性系统性红斑狼疮
Cureus. 2023 Sep 22;15(9):e45800. doi: 10.7759/cureus.45800. eCollection 2023 Sep.
10
Cutaneous manifestations of systemic lupus erythematosus.系统性红斑狼疮的皮肤表现
Br J Dermatol. 1996 Sep;135(3):355-62.

本文引用的文献

1
Bullous lupus as the first manifestation of systemic lupus erythematosus in the pediatric population: A diagnostic challenge in daily practice.儿童系统性红斑狼疮以大疱性狼疮为首发表现 1 例并文献复习：日常诊疗中的诊断挑战。
Lupus. 2020 Dec;29(14):1937-1942. doi: 10.1177/0961203320950814. Epub 2020 Aug 25.
2
Bullous systemic lupus erythematosus - a case report.大疱性系统性红斑狼疮——病例报告
Autops Case Rep. 2019 Feb 25;9(1):e2018069. doi: 10.4322/acr.2018.069. eCollection 2019 Jan-Mar.
3
Rituximab therapy for refractory autoimmune bullous diseases: A multicenter, open-label, single-arm, phase 1/2 study on 10 Japanese patients.
利妥昔单抗治疗难治性自身免疫性大疱性疾病：10 例日本患者的多中心、开放标签、单臂、1/2 期研究。
J Dermatol. 2019 Feb;46(2):124-130. doi: 10.1111/1346-8138.14732. Epub 2018 Dec 26.
4
Bullous systemic lupus erythematosus.大疱性系统性红斑狼疮
Presse Med. 2018 Feb;47(2):190-191. doi: 10.1016/j.lpm.2017.11.021. Epub 2018 Feb 23.
5
Cutaneous Lupus Erythematosus: An Update on Pathogenesis, Diagnosis and Treatment.皮肤红斑狼疮：发病机制、诊断和治疗的最新进展。
Am J Clin Dermatol. 2016 Apr;17(2):135-46. doi: 10.1007/s40257-016-0173-9.
6
Pathophysiology of cutaneous lupus erythematosus.皮肤型红斑狼疮的病理生理学
Arthritis Res Ther. 2015 Aug 10;17(1):182. doi: 10.1186/s13075-015-0706-2.
7
Bullous systemic lupus erythematosus: a review and update to diagnosis and treatment.大疱性系统性红斑狼疮：诊断与治疗的综述及更新
Am J Clin Dermatol. 2014 Dec;15(6):517-24. doi: 10.1007/s40257-014-0098-0.
8
Childhood-onset bullous systemic lupus erythematosus.儿童期起病的大疱性系统性红斑狼疮。
Lupus. 2014 Nov;23(13):1422-5. doi: 10.1177/0961203314544187. Epub 2014 Jul 29.
9
Manifestations of systemic lupus erythematosus.系统性红斑狼疮的临床表现。
Maedica (Bucur). 2011 Oct;6(4):330-6.
10
Multiple blisters along the lip vermilion are a clue to bullous lupus erythematosus.沿唇红缘出现的多个水疱是大疱性红斑狼疮的一个线索。
Acta Derm Venereol. 2012 Jul;92(4):404-5. doi: 10.2340/00015555-1276.