Sampath Shrikanth, Khedr Anwar, Qamar Shahraz, Tekin Aysun, Singh Romil, Green Ronya, Kashyap Rahul
Cardiovascular Medicine, Mayo Clinic, Rochester, USA.
Division of Critical Care Medicine, Mayo Clinic, Mankato, USA.
Cureus. 2021 Sep 20;13(9):e18136. doi: 10.7759/cureus.18136. eCollection 2021 Sep.
As we move amidst the coronavirus disease 2019 (COVID-19) pandemic, we have witnessed tremendous distress, death, and turmoil of everyday life for more than one year now. However, they are not modern phenomena; deadly pandemics have happened throughout recorded history. Pandemics such as the plague, Spanish Flu, HIV, and Ebola caused deaths, destruction of political regimes, as well as financial and psychosocial burdens. However, they sometimes resulted in scientific discoveries. Understanding the mechanism of the emergence of these pandemics is crucial to control any spreading pandemic and prevent the emergence of a potential new one. Public health agencies need to work on improving the countries' pandemic preparedness to prevent any future pandemics. The review article aims to shed light on some of the deadliest pandemics throughout history, information of critical importance for clinicians and researchers.
在我们身处2019冠状病毒病（COVID-19）大流行之中时，至今一年多来，我们目睹了巨大的痛苦、死亡以及日常生活的混乱。然而，这些并非现代才有的现象；致命的大流行在有记录的历史中一直都有发生。诸如鼠疫、西班牙流感、艾滋病毒和埃博拉等大流行造成了死亡、政治政权的破坏以及经济和社会心理负担。然而，它们有时也带来了科学发现。了解这些大流行的出现机制对于控制任何正在蔓延的大流行以及预防潜在新大流行的出现至关重要。公共卫生机构需要致力于提高各国对大流行的防范能力，以预防未来的任何大流行。这篇综述文章旨在阐明历史上一些最致命的大流行，这些信息对临床医生和研究人员至关重要。
