Yan Zhipeng, Yang Ming, Lai Ching-Lung
Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Vaccines (Basel). 2021 Sep 28;9(10):1097. doi: 10.3390/vaccines9101097.
COVID-19 has been spreading worldwide since late 2019. There is no definitive cure to date. Global vaccination programs are urgently required to confer herd immunity, reducing the incidence of COVID-19 infections and associated morbidity and mortality. However, a significant proportion of special populations are hesitant to receive vaccination due to their special conditions, namely, age (pediatrics and geriatrics), immunocompromised state, autoimmune diseases, chronic cardiovascular and pulmonary conditions, active or treated cancers, and pregnancy. This review aims to evaluate the existing evidence of COVID-19 vaccinations on these special populations and to provide clues to guide vaccination decision making to balance the benefits and risks of vaccinations.
自2019年末以来，新冠病毒病（COVID-19）一直在全球范围内传播。迄今为止尚无确切的治愈方法。迫切需要全球疫苗接种计划来实现群体免疫，降低COVID-19感染率以及相关的发病率和死亡率。然而，相当一部分特殊人群因其特殊状况而对接种疫苗犹豫不决，这些特殊状况包括年龄（儿科和老年科）、免疫功能低下状态、自身免疫性疾病、慢性心血管和肺部疾病、活动性癌症或已接受治疗的癌症以及妊娠。本综述旨在评估关于这些特殊人群接种COVID-19疫苗的现有证据，并提供线索以指导疫苗接种决策，平衡疫苗接种的益处和风险。
