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鉴定澳大利亚赛狗中的犬冠状病毒。

Identification of a canine coronavirus in Australian racing Greyhounds.

机构信息

Department of Agriculture and Fisheries, Biosecurity Queensland, Biosecurity Sciences Laboratory, Coopers Plains, Queensland, Australia.

Queensland Racing Integrity Commission, Albion, Queensland, Australia.

出版信息

J Vet Diagn Invest. 2022 Jan;34(1):77-81. doi: 10.1177/10406387211054819. Epub 2021 Oct 26.

Abstract

Coronavirus infection can cause a range of syndromes, which in dogs can include mild-to-severe enteritis that generally resolves rapidly. Fatalities can occur from coinfection with other pathogens, including canine parvovirus. Between late December 2019 and April 2020, canine coronavirus (CCoV) was detected in Australian racing Greyhounds that displayed signs of gastrointestinal disease. The CCoV was genotyped using high-throughput sequencing, recovering 98.3% of a type IIb CCoV, generally thought to cause a mild but highly contagious enteric disease. The Australian CCoV was almost identical (99.9%, whole-genome sequence) to another CCoV associated with an outbreak of severe vomiting in dogs in the United Kingdom at the same time (December 2019-March 2020).

摘要

冠状病毒感染可引起多种综合征,在犬中可包括轻度至重度肠炎,通常迅速消退。继发感染其他病原体(包括犬细小病毒)可导致死亡。2019 年 12 月底至 2020 年 4 月,在出现胃肠道疾病症状的澳大利亚赛狗中检测到犬冠状病毒(CCoV)。使用高通量测序对 CCoV 进行基因分型,恢复了 98.3%的 IIb 型 CCoV,通常认为该病毒可引起轻度但高度传染性的肠道疾病。澳大利亚 CCoV 与同时在英国暴发的另一种与严重呕吐相关的 CCoV (2019 年 12 月至 2020 年 3 月)几乎完全相同(99.9%,全基因组序列)。

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